ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000042046 Dstyk 10090 + 1:132417555-132466958 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000045110 Dstyk-001 132417555-132466958 protein_coding
  ENSMUST00000187092 Dstyk-007 132449398-132451607 protein_coding
  ENSMUST00000188006 Dstyk-005 132454575-132457639 retained_intron
  ENSMUST00000188389 Dstyk-004 132417604-132464092 protein_coding
  ENSMUST00000188973 Dstyk-006 132418377-132434148 processed_transcript
  ENSMUST00000191494 Dstyk-008 132462409-132463356 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000045110ENSMUST00000188389
Transcript ID C166 Tie2+ EC mES
ENSMUST00000045110 7.950±1.74 2.982±0.88 0.910±0.30
ENSMUST00000188389 N/A 4.629±0.10 N/A

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004712 IEA protein serine/threonine/tyrosine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005524 IEA ATP binding
GO:0005737 IDA cytoplasm
GO:0016323 IDA basolateral plasma membrane
GO:0016324 IDA apical plasma membrane
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0033674 ISS positive regulation of kinase activity
GO:0044344 ISS cellular response to fibroblast growth factor stimulus
GO:0045743 ISS positive regulation of fibroblast growth factor receptor signaling pathway
GO:0070374 ISS positive regulation of ERK1 and ERK2 cascade

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000000853 dstyk protein_coding Danio_rerio
ENSG00000133059 DSTYK dual serine/threonine and tyrosine protein kinase protein_coding Homo_sapiens

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