ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: microtubule associated monooxygenase, calponin and LIM domain containing 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000133816 MICAL2 9606 + 11:12094008-12263789 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000256194 MICAL2-001 12110591-12263785 protein_coding
  ENST00000342902 MICAL2-201 12138390-12263789 protein_coding
  ENST00000379612 MICAL2-202 12162079-12263789 protein_coding
  ENST00000524685 MICAL2-023 12161443-12204347 protein_coding
  ENST00000524730 MICAL2-020 12213255-12216393 retained_intron
  ENST00000525075 MICAL2-013 12239460-12257233 retained_intron
  ENST00000525119 MICAL2-024 12161446-12204387 protein_coding
  ENST00000525216 MICAL2-015 12242182-12242984 processed_transcript
  ENST00000525444 MICAL2-017 12259689-12263781 retained_intron
  ENST00000525618 MICAL2-004 12252532-12263787 retained_intron
  ENST00000525979 MICAL2-027 12243200-12256968 processed_transcript
  ENST00000526065 MICAL2-026 12094017-12162420 protein_coding
  ENST00000526475 MICAL2-014 12226207-12244034 processed_transcript
  ENST00000526604 MICAL2-012 12256842-12260748 processed_transcript
  ENST00000526672 MICAL2-016 12249941-12256909 processed_transcript
  ENST00000527195 MICAL2-019 12195945-12208146 processed_transcript
  ENST00000527546 MICAL2-007 12138388-12262919 protein_coding
  ENST00000528931 MICAL2-006 12162156-12260172 retained_intron
  ENST00000529562 MICAL2-021 12225585-12227098 processed_transcript
  ENST00000530021 MICAL2-005 12253234-12263782 retained_intron
  ENST00000530691 MICAL2-003 12207725-12263785 retained_intron
  ENST00000530823 MICAL2-011 12116696-12162166 protein_coding
  ENST00000531732 MICAL2-002 12110605-12208369 retained_intron
  ENST00000532166 MICAL2-018 12195945-12197811 processed_transcript
  ENST00000532179 MICAL2-008 12094008-12204280 protein_coding
  ENST00000532420 MICAL2-010 12121475-12162419 protein_coding
  ENST00000532945 MICAL2-009 12094128-12096221 processed_transcript
  ENST00000533219 MICAL2-022 12224438-12227193 retained_intron
  ENST00000533389 MICAL2-025 12161868-12204290 protein_coding
  ENST00000534563 MICAL2-028 12242321-12259942 processed_transcript
  ENST00000537344 MICAL2-203 12138390-12263789 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000379612ENST00000525444ENST00000527546ENST00000528931ENST00000530021ENST00000530691
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000379612 4.470±0.00 47.588±20.73 N/A 9.491±0.00 11.129±5.59
ENST00000525444 88.404±14.29 N/A N/A N/A N/A
ENST00000527546 N/A N/A N/A N/A 0.020±0.00
ENST00000528931 N/A 20.879±11.23 N/A 12.771±0.00 9.837±1.62
ENST00000530021 N/A N/A N/A N/A 3.307±0.00
ENST00000530691 N/A 12.304±6.60 0.354±0.00 N/A 7.759±3.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0008T3 CIL_0008T3_0001 VISTA
CIL_0008YS CIL_0008YS_0001 VISTA
CIL_0007SQ CIL_0007SQ_0001 VISTA
CIL_0004J2 CIL_0004J2_0001 CGP
CIL_0004J1 CIL_0004J1_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001947 ISS heart looping
GO:0003779 ISS actin binding
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0007010 IDA cytoskeleton organization
GO:0007507 ISS heart development
GO:0008270 IEA zinc ion binding
GO:0010735 IMP positive regulation of transcription via serum response element binding
GO:0016491 IEA oxidoreductase activity
GO:0016709 ISS oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
GO:0019417 ISS sulfur oxidation
GO:0030042 ISS actin filament depolymerization
GO:0043914 IDA NADPH:sulfur oxidoreductase activity
GO:0050660 IEA flavin adenine dinucleotide binding
GO:0055114 ISS oxidation-reduction process
GO:0071949 ISS FAD binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020395 mical2b protein_coding Danio_rerio
ENSDARG00000075608 mical2a protein_coding Danio_rerio
ENSMUSG00000038244 Mical2 protein_coding Mus_musculus

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