ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: complement component 5a receptor 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000134830 C5AR2 9606 + 19:47332147-47347327 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000595464 C5AR2-001 47332147-47347327 protein_coding
  ENST00000600626 C5AR2-002 47337114-47342015 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000595464ENST00000600626
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000595464 0.136±0.05 0.076±0.04 0.867±0.00 0.266±0.00 0.074±0.07
ENST00000600626 N/A N/A N/A N/A 0.111±0.09

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0008G1 CIL_0008G1_0001 VISTA

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004930 IEA G-protein coupled receptor activity
GO:0004944 IEA C5a anaphylatoxin receptor activity
GO:0005515 IPI protein binding
GO:0005886 TAS plasma membrane
GO:0006935 IEA chemotaxis
GO:0006954 IEA inflammatory response
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0009925 IDA basal plasma membrane
GO:0016021 IEA integral component of membrane
GO:0032720 IMP negative regulation of tumor necrosis factor production
GO:0045177 IDA apical part of cell
GO:0050679 IEA positive regulation of epithelial cell proliferation
GO:0070374 IEA positive regulation of ERK1 and ERK2 cascade
GO:0090024 IMP negative regulation of neutrophil chemotaxis
GO:1900165 IMP negative regulation of interleukin-6 secretion
GO:2000482 IMP regulation of interleukin-8 secretion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000040319 c5ar1 protein_coding Danio_rerio
ENSMUSG00000074361 C5ar2 protein_coding Mus_musculus

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