ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: complement component 5a receptor 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000595464 C5AR2-001 ENSG00000134830 9606 + 19:47332147-47347327 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000595464
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000595464 0.136±0.05 0.076±0.04 0.867±0.00 0.266±0.00 0.074±0.07

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004930 IEA G-protein coupled receptor activity
GO:0004944 IEA C5a anaphylatoxin receptor activity
GO:0005515 IPI protein binding
GO:0005886 TAS plasma membrane
GO:0006935 IEA chemotaxis
GO:0006954 IEA inflammatory response
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0009925 IDA basal plasma membrane
GO:0016021 IEA integral component of membrane
GO:0032720 IMP negative regulation of tumor necrosis factor production
GO:0045177 IDA apical part of cell
GO:0050679 IEA positive regulation of epithelial cell proliferation
GO:0070374 IEA positive regulation of ERK1 and ERK2 cascade
GO:0090024 IMP negative regulation of neutrophil chemotaxis
GO:1900165 IMP negative regulation of interleukin-6 secretion
GO:2000482 IMP regulation of interleukin-8 secretion

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000034431 Tmem170-201 protein_coding Mus_musculus 0.00000002 68
ENSMUST00000146544 Golga2-011 retained_intron Mus_musculus 0.0004 53

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