ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: cadherin 13
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000140945 CDH13 9606 + 16:82626803-83800640 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000268613 CDH13-009 82626965-83795376 protein_coding
  ENST00000428848 CDH13-005 82626970-83795077 protein_coding
  ENST00000431540 CDH13-003 82626970-83181094 protein_coding
  ENST00000539548 CDH13-006 82626970-83795173 nonsense_mediated_decay
  ENST00000562307 CDH13-016 83654820-83670881 processed_transcript
  ENST00000562601 CDH13-011 82626968-83032059 nonsense_mediated_decay
  ENST00000565636 CDH13-004 82626970-83181025 protein_coding
  ENST00000566333 CDH13-014 82626971-83032313 retained_intron
  ENST00000566620 CDH13-201 82858356-83796608 protein_coding
  ENST00000567109 CDH13-001 82626803-83800640 protein_coding
  ENST00000567445 CDH13-007 82627039-82859718 protein_coding
  ENST00000568770 CDH13-013 82626969-83032121 nonsense_mediated_decay
  ENST00000569144 CDH13-012 82626966-83032144 nonsense_mediated_decay
  ENST00000569454 CDH13-015 82925958-83486655 processed_transcript
  ENST00000569455 CDH13-010 82627039-82723105 processed_transcript
  ENST00000615627 CDH13-202 83670578-83796608 protein_coding
  ENST00000622885 CDH13-203 82858356-83796608 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000428848ENST00000431540ENST00000539548ENST00000566333ENST00000566620ENST00000615627ENST00000622885
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000428848 N/A N/A N/A N/A 21.211±14.72
ENST00000431540 8.303±0.00 N/A N/A N/A N/A
ENST00000539548 N/A N/A N/A N/A 17.454±6.44
ENST00000566333 N/A N/A N/A N/A 60.496±16.00
ENST00000566620 2.901±0.00 25.948±7.22 N/A 77.667±0.00 23.615±13.96
ENST00000615627 14.836±3.49 8.902±1.80 1.023±0.00 N/A 14.363±8.60
ENST00000622885 N/A N/A 0.243±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0003NV CIL_0003NV_0001 CGP
CIL_0008L6 CIL_0008L6_0001 VISTA
CIL_0005JS CIL_0005JS_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001938 IMP positive regulation of endothelial cell proliferation
GO:0001954 IMP positive regulation of cell-matrix adhesion
GO:0002040 IDA sprouting angiogenesis
GO:0005509 IEA calcium ion binding
GO:0005515 IEA protein binding
GO:0005615 IDA extracellular space
GO:0005737 IDA cytoplasm
GO:0005886 IDA plasma membrane
GO:0005901 IDA caveola
GO:0005925 IDA focal adhesion
GO:0007156 IDA:IEA homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007162 IDA negative regulation of cell adhesion
GO:0007266 IMP Rho protein signal transduction
GO:0008285 IDA negative regulation of cell proliferation
GO:0009897 IEA external side of plasma membrane
GO:0016020 IEA membrane
GO:0016339 IDA calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0016601 IMP Rac protein signal transduction
GO:0030032 IDA lamellipodium assembly
GO:0030100 IMP regulation of endocytosis
GO:0030169 IDA low-density lipoprotein particle binding
GO:0030335 IDA positive regulation of cell migration
GO:0031225 IEA anchored component of membrane
GO:0034329 TAS cell junction assembly
GO:0034332 TAS adherens junction organization
GO:0042058 IMP regulation of epidermal growth factor receptor signaling pathway
GO:0042803 IEA protein homodimerization activity
GO:0043005 IDA neuron projection
GO:0043542 IDA endothelial cell migration
GO:0043616 IDA keratinocyte proliferation
GO:0045216 TAS cell-cell junction organization
GO:0045296 IDA cadherin binding
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0048661 IMP positive regulation of smooth muscle cell proliferation
GO:0050850 IDA positive regulation of calcium-mediated signaling
GO:0050927 IDA positive regulation of positive chemotaxis
GO:0051668 IMP localization within membrane
GO:0055096 IDA low-density lipoprotein particle mediated signaling
GO:0055100 ISS adiponectin binding
GO:0070062 IDA extracellular vesicular exosome
GO:0071813 IDA lipoprotein particle binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014215 cdh13 protein_coding Danio_rerio
ENSMUSG00000031841 Cdh13 protein_coding Mus_musculus

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