ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: growth factor receptor-bound protein 7
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000141738 GRB7 9606 + 17:39737927-39747291 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000309156 GRB7-001 39737927-39747284 protein_coding
  ENST00000394204 GRB7-003 39742252-39747003 protein_coding
  ENST00000394209 GRB7-009 39739967-39746988 protein_coding
  ENST00000394211 GRB7-002 39738337-39747285 protein_coding
  ENST00000445327 GRB7-006 39738771-39747291 protein_coding
  ENST00000461756 GRB7-004 39742934-39743612 retained_intron
  ENST00000473071 GRB7-007 39743272-39744428 retained_intron
  ENST00000485182 GRB7-005 39737949-39743054 retained_intron
  ENST00000577695 GRB7-011 39737927-39742922 protein_coding
  ENST00000578702 GRB7-014 39738353-39744103 processed_transcript
  ENST00000583813 GRB7-012 39737962-39743281 nonsense_mediated_decay
  ENST00000584053 GRB7-013 39740132-39742894 retained_intron
  ENST00000584819 GRB7-008 39738306-39744604 retained_intron
  ENST00000584853 GRB7-010 39737974-39738982 processed_transcript

Homo sapiens Ensembl GRCh38

Genome
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Sequences
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Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHUVECENST00000309156ENST00000394204ENST00000394209ENST00000394211ENST00000445327ENST00000461756ENST00000473071ENST00000485182ENST00000577695ENST00000578702ENST00000583813ENST00000584053ENST00000584819ENST00000584853
Transcript ID BECs HAoEC HHSEC HUVEC
ENST00000309156 N/A 0.407±0.20 N/A 0.057±0.02
ENST00000394204 N/A 0.276±0.00 0.117±0.00 0.064±0.08
ENST00000394209 N/A 0.006±0.00 N/A 0.037±0.00
ENST00000394211 0.017±0.00 0.244±0.18 0.129±0.00 0.021±0.01
ENST00000445327 N/A 0.126±0.11 N/A 0.040±0.02
ENST00000461756 N/A N/A N/A 0.082±0.00
ENST00000473071 N/A 0.235±0.00 N/A N/A
ENST00000485182 N/A N/A 0.093±0.00 N/A
ENST00000577695 N/A 0.521±0.00 N/A 0.079±0.00
ENST00000578702 N/A 0.380±0.00 N/A 0.120±0.00
ENST00000583813 N/A 0.033±0.00 N/A 0.093±0.03
ENST00000584053 N/A N/A N/A 0.096±0.04
ENST00000584819 N/A N/A N/A 0.027±0.00
ENST00000584853 N/A 0.103±0.07 N/A N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00080Z CIL_00080Z_0001 VISTA
CIL_00098W CIL_00098W_0001 VISTA
CIL_0007WH CIL_0007WH_0001 VISTA
CIL_0002E0 CIL_0002E0_0001 CGP
CIL_0002PT CIL_0002PT_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003723 IEA RNA binding
GO:0005070 TAS SH3/SH2 adaptor activity
GO:0005515 IPI protein binding
GO:0005829 IDA cytosol
GO:0005886 IEA plasma membrane
GO:0005925 IDA focal adhesion
GO:0007165 IEA signal transduction
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007596 TAS blood coagulation
GO:0009967 TAS positive regulation of signal transduction
GO:0010494 ISS cytoplasmic stress granule
GO:0017148 ISS negative regulation of translation
GO:0019901 IDA protein kinase binding
GO:0030335 IDA positive regulation of cell migration
GO:0034063 ISS stress granule assembly
GO:0035091 IDA phosphatidylinositol binding
GO:0042802 IPI identical protein binding
GO:0042995 IEA cell projection
GO:0050900 TAS leukocyte migration

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042726 GRB7 protein_coding Danio_rerio
ENSMUSG00000019312 Grb7 protein_coding Mus_musculus

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