ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000019312 Grb7 10090 + 11:98446394-98455373 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000019456 Grb7-001 98446834-98455373 protein_coding
  ENSMUST00000127914 Grb7-006 98447048-98455373 retained_intron
  ENSMUST00000129034 Grb7-003 98453789-98455125 retained_intron
  ENSMUST00000132771 Grb7-002 98446394-98451417 protein_coding
  ENSMUST00000133419 Grb7-004 98451842-98453822 retained_intron
  ENSMUST00000156328 Grb7-005 98447068-98455373 retained_intron

Mus musculus Ensembl GRCm38

Genome
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Sequences
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Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000019456ENSMUST00000127914ENSMUST00000129034ENSMUST00000132771ENSMUST00000133419ENSMUST00000156328
Transcript ID C166 Tie2+ EC mES
ENSMUST00000019456 0.033±0.01 7.171±0.26 0.669±0.26
ENSMUST00000127914 0.028±0.00 2.001±1.43 N/A
ENSMUST00000129034 0.027±0.01 N/A N/A
ENSMUST00000132771 0.078±0.00 N/A N/A
ENSMUST00000133419 0.055±0.00 0.144±0.00 N/A
ENSMUST00000156328 0.028±0.00 0.015±0.00 0.250±0.08

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0008SN CIL_0008SN_0002 VISTA
CIL_00080Z CIL_00080Z_0002 VISTA
CIL_00098W CIL_00098W_0002 VISTA
CIL_0007WH CIL_0007WH_0002 VISTA
CIL_0002E0 CIL_0002E0_0002 CGP
CIL_0002PT CIL_0002PT_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003723 IEA RNA binding
GO:0005070 TAS SH3/SH2 adaptor activity
GO:0005515 IPI protein binding
GO:0005829 TAS:ISS cytosol
GO:0005886 IEA plasma membrane
GO:0005925 ISS focal adhesion
GO:0007165 TAS signal transduction
GO:0009967 TAS positive regulation of signal transduction
GO:0010494 IDA cytoplasmic stress granule
GO:0017148 IMP negative regulation of translation
GO:0019901 IEA protein kinase binding
GO:0030335 ISS positive regulation of cell migration
GO:0034063 IMP stress granule assembly
GO:0035091 ISS phosphatidylinositol binding
GO:0042802 IEA identical protein binding
GO:0042995 IEA cell projection

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042726 GRB7 protein_coding Danio_rerio
ENSG00000141738 GRB7 growth factor receptor-bound protein 7 protein_coding Homo_sapiens

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