ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: denticleless E3 ubiquitin protein ligase homolog (Drosophila)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000143476 DTL 9606 + 1:212035553-212107400 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000366991 DTL-001 212035577-212105006 protein_coding
  ENST00000463791 DTL-004 212080369-212100426 processed_transcript
  ENST00000475419 DTL-002 212035846-212104594 processed_transcript
  ENST00000489149 DTL-003 212072074-212100700 processed_transcript
  ENST00000496442 DTL-005 212100646-212107400 processed_transcript
  ENST00000542077 DTL-201 212035553-212105006 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000366991ENST00000475419ENST00000489149ENST00000496442ENST00000542077
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000366991 N/A 4.450±1.67 N/A 2.475±0.00 2.688±1.78
ENST00000475419 N/A N/A N/A 1.029±0.00 0.865±0.54
ENST00000489149 N/A N/A N/A N/A 1.283±0.31
ENST00000496442 3.035±0.00 N/A N/A N/A N/A
ENST00000542077 1.214±0.00 N/A 0.343±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_000128 CIL_000128_0002 CGP
CIL_000129 CIL_000129_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000209 TAS protein polyubiquitination
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005694 IEA chromosome
GO:0005730 IDA nucleolus
GO:0005737 IDA cytoplasm
GO:0005813 IDA centrosome
GO:0006260 IEA DNA replication
GO:0006511 TAS ubiquitin-dependent protein catabolic process
GO:0006513 IDA protein monoubiquitination
GO:0006974 IDA cellular response to DNA damage stimulus
GO:0009411 IDA response to UV
GO:0016020 IEA membrane
GO:0019985 IDA translesion synthesis
GO:0031464 IDA Cul4A-RING E3 ubiquitin ligase complex
GO:0031465 IDA Cul4B-RING E3 ubiquitin ligase complex
GO:0031572 IMP G2 DNA damage checkpoint
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0051726 IMP regulation of cell cycle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000023002 dtl protein_coding Danio_rerio
ENSMUSG00000037474 Dtl protein_coding Mus_musculus

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