ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info

Description: denticleless E3 ubiquitin protein ligase homolog (Drosophila)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000366991 DTL-001 ENSG00000143476 9606 + 1:212035577-212105006 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHMVEC-DHUVECENST00000366991
Transcript ID HAoEC HMVEC-D HUVEC
ENST00000366991 4.450±1.67 2.475±0.00 2.688±1.78

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000209 TAS protein polyubiquitination
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005694 IEA chromosome
GO:0005730 IDA nucleolus
GO:0005737 IDA cytoplasm
GO:0005813 IDA centrosome
GO:0006260 IEA DNA replication
GO:0006511 TAS ubiquitin-dependent protein catabolic process
GO:0006513 IDA protein monoubiquitination
GO:0006974 IDA cellular response to DNA damage stimulus
GO:0009411 IDA response to UV
GO:0016020 IEA membrane
GO:0019985 IDA translesion synthesis
GO:0031464 IDA Cul4A-RING E3 ubiquitin ligase complex
GO:0031465 IDA Cul4B-RING E3 ubiquitin ligase complex
GO:0031572 IMP G2 DNA damage checkpoint
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0051726 IMP regulation of cell cycle

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000027933 Dtl-001 protein_coding Mus_musculus 0 2689
ENSMUST00000195765 Dtl-006 processed_transcript Mus_musculus 0 2532
ENSMUST00000195650 Dtl-002 nonsense_mediated_decay Mus_musculus 0 2067
ENSMUST00000193977 Dtl-005 nonsense_mediated_decay Mus_musculus 0 1325
ENSMUST00000194064 Dtl-004 retained_intron Mus_musculus 0 822

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