ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: DIS3 like 3'-5' exoribonuclease 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000144535 DIS3L2 9606 + 2:231961245-232344350 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000273009 DIS3L2-001 231961245-232344350 protein_coding
  ENST00000325385 DIS3L2-201 231961583-232337197 protein_coding
  ENST00000390005 DIS3L2-002 231961684-232337198 nonsense_mediated_decay
  ENST00000409307 DIS3L2-015 232014928-232336630 protein_coding
  ENST00000409401 DIS3L2-003 231961684-232131890 protein_coding
  ENST00000417808 DIS3L2-007 232335785-232336973 protein_coding
  ENST00000418143 DIS3L2-012 232334660-232336974 protein_coding
  ENST00000424049 DIS3L2-010 232163604-232334454 protein_coding
  ENST00000429283 DIS3L2-006 232328508-232336976 retained_intron
  ENST00000433430 DIS3L2-005 232014928-232336977 nonsense_mediated_decay
  ENST00000434477 DIS3L2-011 232333943-232340999 protein_coding
  ENST00000441279 DIS3L2-008 231961708-232087552 protein_coding
  ENST00000445090 DIS3L2-004 231961692-232336555 nonsense_mediated_decay
  ENST00000464554 DIS3L2-013 232015601-232087844 retained_intron
  ENST00000470087 DIS3L2-009 232015852-232130875 processed_transcript
  ENST00000498319 DIS3L2-014 232249340-232307778 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000273009ENST00000325385ENST00000390005ENST00000409307ENST00000409401ENST00000417808ENST00000418143ENST00000424049ENST00000429283ENST00000441279ENST00000445090
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000273009 N/A N/A N/A N/A 0.712±0.17
ENST00000325385 1.949±0.13 2.051±0.62 N/A 4.927±0.00 3.009±2.33
ENST00000390005 0.963±0.00 3.157±0.78 1.431±0.00 N/A 1.554±0.74
ENST00000409307 N/A 4.686±1.23 N/A N/A 2.400±1.22
ENST00000409401 N/A 1.860±0.00 N/A N/A 1.305±0.00
ENST00000417808 N/A N/A 7.443±0.00 N/A N/A
ENST00000418143 8.117±1.09 N/A 10.392±0.00 N/A N/A
ENST00000424049 4.534±0.00 4.854±0.00 N/A N/A 3.492±1.88
ENST00000429283 N/A N/A N/A N/A 0.314±0.02
ENST00000441279 N/A N/A N/A N/A 6.833±1.33
ENST00000445090 N/A N/A N/A N/A 3.514±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_000899 CIL_000899_0001 VISTA
CIL_0007WD CIL_0007WD_0001 VISTA
CIL_0007FN CIL_0007FN_0001 CGP
CIL_0007FQ CIL_0007FQ_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000175 IDA 3'-5'-exoribonuclease activity
GO:0000287 IDA magnesium ion binding
GO:0000291 IMP nuclear-transcribed mRNA catabolic process, exonucleolytic
GO:0000932 IDA cytoplasmic mRNA processing body
GO:0004540 IDA ribonuclease activity
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005844 TAS polysome
GO:0007067 IMP mitotic nuclear division
GO:0008266 IDA poly(U) RNA binding
GO:0008285 IMP negative regulation of cell proliferation
GO:0010587 ISS miRNA catabolic process
GO:0019827 ISS stem cell maintenance
GO:0034427 IEA nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'
GO:0051306 IMP mitotic sister chromatid separation
GO:0090501 IDA RNA phosphodiester bond hydrolysis
GO:0090503 IEA RNA phosphodiester bond hydrolysis, exonucleolytic
GO:1990074 ISS polyuridylation-dependent mRNA catabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000033259 dis3l2 protein_coding Danio_rerio
ENSMUSG00000053333 Dis3l2 protein_coding Mus_musculus

Loading