ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000053333 Dis3l2 10090 + 1:86703808-87050095 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000065694 Dis3l2-002 86703843-87050092 protein_coding
  ENSMUST00000168237 Dis3l2-001 86703819-87050095 protein_coding
  ENSMUST00000186682 Dis3l2-006 86857371-86858105 retained_intron
  ENSMUST00000188121 Dis3l2-004 86703808-86748331 processed_transcript
  ENSMUST00000189044 Dis3l2-005 86703828-86882439 retained_intron
  ENSMUST00000190618 Dis3l2-003 86703828-87049195 nonsense_mediated_decay

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000065694ENSMUST00000168237
Transcript ID C166 Tie2+ EC mES
ENSMUST00000065694 2.470±0.69 3.058±1.65 4.174±0.85
ENSMUST00000168237 0.740±0.17 1.523±0.85 4.774±0.09

Conserved Regions

Region IDSub-RegionRegion Type
CIL_000899 CIL_000899_0002 VISTA
CIL_0007WD CIL_0007WD_0002 VISTA
CIL_0007FN CIL_0007FN_0002 CGP
CIL_0007FQ CIL_0007FQ_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000175 IDA 3'-5'-exoribonuclease activity
GO:0000287 IDA magnesium ion binding
GO:0000291 ISS nuclear-transcribed mRNA catabolic process, exonucleolytic
GO:0000932 ISS cytoplasmic mRNA processing body
GO:0004540 ISS ribonuclease activity
GO:0005515 IEA protein binding
GO:0005737 ISS cytoplasm
GO:0007067 ISS mitotic nuclear division
GO:0008266 IDA poly(U) RNA binding
GO:0008285 ISS negative regulation of cell proliferation
GO:0010587 IMP miRNA catabolic process
GO:0019827 IMP stem cell maintenance
GO:0034427 IEA nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'
GO:0051306 ISS mitotic sister chromatid separation
GO:0090501 IEA RNA phosphodiester bond hydrolysis
GO:0090503 IEA RNA phosphodiester bond hydrolysis, exonucleolytic
GO:1990074 ISS polyuridylation-dependent mRNA catabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000033259 dis3l2 protein_coding Danio_rerio
ENSG00000144535 DIS3L2 DIS3 like 3'-5' exoribonuclease 2 protein_coding Homo_sapiens

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