ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: metadherin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000147649 MTDH 9606 + 8:97644179-97728770 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000336273 MTDH-001 97644179-97728770 protein_coding
  ENST00000519293 MTDH-004 97691019-97724652 nonsense_mediated_decay
  ENST00000519934 MTDH-002 97644546-97725243 protein_coding
  ENST00000521933 MTDH-006 97691131-97724617 protein_coding
  ENST00000522104 MTDH-005 97706412-97719087 retained_intron
  ENST00000522313 MTDH-003 97644793-97691164 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000336273ENST00000519293ENST00000519934
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000336273 3.270±0.00 10.164±6.46 0.642±0.00 8.323±0.00 11.561±8.20
ENST00000519293 N/A N/A N/A N/A 38.242±5.56
ENST00000519934 N/A 7.801±2.20 N/A 16.342±0.00 14.466±7.43

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0001L2 CIL_0001L2_0001 CGP
CIL_0001KW CIL_0001KW_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0001085 IPI RNA polymerase II transcription factor binding
GO:0003713 IMP transcription coactivator activity
GO:0003725 IDA double-stranded RNA binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005730 IDA nucleolus
GO:0005737 IDA cytoplasm
GO:0005783 IDA endoplasmic reticulum
GO:0005789 ISS endoplasmic reticulum membrane
GO:0005923 ISS tight junction
GO:0010508 IDA positive regulation of autophagy
GO:0016021 IEA integral component of membrane
GO:0016324 ISS apical plasma membrane
GO:0016604 IDA nuclear body
GO:0031663 IMP lipopolysaccharide-mediated signaling pathway
GO:0043066 IDA negative regulation of apoptotic process
GO:0043123 IDA positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0044822 IDA poly(A) RNA binding
GO:0045766 IDA positive regulation of angiogenesis
GO:0046581 ISS intercellular canaliculus
GO:0048471 IDA perinuclear region of cytoplasm
GO:0051059 IPI NF-kappaB binding
GO:0051092 IDA positive regulation of NF-kappaB transcription factor activity
GO:0051897 IDA positive regulation of protein kinase B signaling
GO:0070830 IEA tight junction assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000004939 mtdhb protein_coding Danio_rerio
ENSDARG00000014159 mtdha protein_coding Danio_rerio
ENSMUSG00000022255 Mtdh protein_coding Mus_musculus

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