ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000022255 Mtdh 10090 + 15:34082694-34142386 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000022865 Mtdh-001 34082719-34142386 protein_coding
  ENSMUST00000163333 Mtdh-005 34083308-34136780 protein_coding
  ENSMUST00000163697 Mtdh-003 34082725-34124352 retained_intron
  ENSMUST00000168991 Mtdh-010 34083036-34134344 nonsense_mediated_decay
  ENSMUST00000169905 Mtdh-006 34114942-34140710 protein_coding
  ENSMUST00000170050 Mtdh-008 34083319-34136811 protein_coding
  ENSMUST00000170553 Mtdh-009 34083322-34123750 protein_coding
  ENSMUST00000171711 Mtdh-004 34133490-34141283 processed_transcript
  ENSMUST00000172082 Mtdh-002 34082694-34103345 retained_intron
  ENSMUST00000172083 Mtdh-007 34083853-34117997 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000022865ENSMUST00000163333ENSMUST00000168991ENSMUST00000169905ENSMUST00000170050
Transcript ID C166 Tie2+ EC mES
ENSMUST00000022865 40.966±12.48 18.363±6.42 8.586±1.39
ENSMUST00000163333 32.584±0.00 N/A N/A
ENSMUST00000168991 N/A 29.404±0.00 N/A
ENSMUST00000169905 N/A 33.909±7.74 N/A
ENSMUST00000170050 N/A N/A 12.944±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0001L2 CIL_0001L2_0002 CGP
CIL_0001KW CIL_0001KW_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0001085 IEA RNA polymerase II transcription factor binding
GO:0003713 IEA transcription coactivator activity
GO:0003725 ISO double-stranded RNA binding
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005730 IDA nucleolus
GO:0005737 IEA cytoplasm
GO:0005783 ISS endoplasmic reticulum
GO:0005789 IDA endoplasmic reticulum membrane
GO:0005923 IEA tight junction
GO:0010508 IEA positive regulation of autophagy
GO:0016021 IEA integral component of membrane
GO:0016324 IEA apical plasma membrane
GO:0016604 IEA nuclear body
GO:0031663 IEA lipopolysaccharide-mediated signaling pathway
GO:0043066 IEA negative regulation of apoptotic process
GO:0043123 IEA positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0044822 IEA poly(A) RNA binding
GO:0045766 IEA positive regulation of angiogenesis
GO:0046581 IEA intercellular canaliculus
GO:0048471 ISS perinuclear region of cytoplasm
GO:0051059 ISS NF-kappaB binding
GO:0051092 ISS positive regulation of NF-kappaB transcription factor activity
GO:0051897 IEA positive regulation of protein kinase B signaling
GO:0070830 IEA tight junction assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000004939 mtdhb protein_coding Danio_rerio
ENSDARG00000014159 mtdha protein_coding Danio_rerio
ENSG00000147649 MTDH metadherin protein_coding Homo_sapiens

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