ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: prostaglandin E synthase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000148344 PTGES 9606 - 9:129738331-129753047 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000340607 PTGES-001 129738331-129753047 protein_coding
  ENST00000481476 PTGES-002 129738331-129753019 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000340607ENST00000481476
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000340607 0.440±0.13 1.843±1.39 0.067±0.00 0.174±0.00 0.052±0.03
ENST00000481476 N/A 0.305±0.24 N/A N/A 0.102±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0005UC CIL_0005UC_0001 CGP
CIL_0005UB CIL_0005UB_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001516 IDA prostaglandin biosynthetic process
GO:0002526 IEA acute inflammatory response
GO:0002544 IEA chronic inflammatory response
GO:0005641 IEA nuclear envelope lumen
GO:0005737 IEA cytoplasm
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006693 TAS prostaglandin metabolic process
GO:0007165 NAS signal transduction
GO:0008285 IEA negative regulation of cell proliferation
GO:0014070 IEA response to organic cyclic compound
GO:0016020 TAS membrane
GO:0016021 IDA integral component of membrane
GO:0019369 TAS arachidonic acid metabolic process
GO:0019371 TAS cyclooxygenase pathway
GO:0032496 IEA response to lipopolysaccharide
GO:0032526 IEA response to retinoic acid
GO:0034097 IEA response to cytokine
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0043295 IDA glutathione binding
GO:0044281 TAS small molecule metabolic process
GO:0048471 IEA perinuclear region of cytoplasm
GO:0050220 IDA prostaglandin-E synthase activity
GO:0051592 IEA response to calcium ion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020136 ptges protein_coding Danio_rerio
ENSMUSG00000050737 Ptges protein_coding Mus_musculus

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