ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: phospholipase C, eta 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000149527 PLCH2 9606 + 1:2425980-2505530 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000278878 PLCH2-002 2479888-2505276 protein_coding
  ENST00000343889 PLCH2-001 2479090-2505530 retained_intron
  ENST00000378486 PLCH2-201 2476315-2505525 protein_coding
  ENST00000419816 PLCH2-009 2476315-2505525 protein_coding
  ENST00000449969 PLCH2-008 2467459-2505526 protein_coding
  ENST00000462379 PLCH2-006 2498647-2505528 retained_intron
  ENST00000473964 PLCH2-005 2497782-2505528 retained_intron
  ENST00000609981 PLCH2-010 2425980-2479804 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000278878ENST00000343889ENST00000378486ENST00000419816ENST00000449969ENST00000462379ENST00000473964ENST00000609981
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000278878 N/A 0.156±0.19 N/A N/A 0.027±0.01
ENST00000343889 0.044±0.00 0.013±0.00 0.027±0.00 0.065±0.00 0.021±0.01
ENST00000378486 N/A 0.508±0.00 N/A N/A 0.025±0.02
ENST00000419816 N/A N/A N/A N/A 0.020±0.01
ENST00000449969 N/A 0.087±0.08 0.019±0.00 N/A 0.029±0.02
ENST00000462379 0.090±0.00 0.033±0.00 0.187±0.00 N/A 0.034±0.02
ENST00000473964 N/A 0.010±0.01 0.035±0.00 N/A 0.009±0.00
ENST00000609981 N/A 0.080±0.00 N/A N/A 0.096±0.01

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0007QV CIL_0007QV_0001 VISTA
CIL_0005YM CIL_0005YM_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003674 ND molecular_function
GO:0004435 IEA phosphatidylinositol phospholipase C activity
GO:0004629 IEA phospholipase C activity
GO:0004871 IEA signal transducer activity
GO:0005509 IEA calcium ion binding
GO:0005515 IEA protein binding
GO:0005575 ND cellular_component
GO:0005737 IEA cytoplasm
GO:0005886 TAS plasma membrane
GO:0006629 IEA lipid metabolic process
GO:0007165 IEA signal transduction
GO:0008081 IEA phosphoric diester hydrolase activity
GO:0008150 ND biological_process
GO:0008152 IEA metabolic process
GO:0016042 IEA lipid catabolic process
GO:0035556 IEA intracellular signal transduction
GO:0043647 TAS inositol phosphate metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0046488 IEA phosphatidylinositol metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000056805 plch2b protein_coding Danio_rerio
ENSDARG00000059960 plch2a protein_coding Danio_rerio
ENSMUSG00000029055 Plch2 protein_coding Mus_musculus

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