ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: twinfilin actin-binding protein 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000151239 TWF1 9606 - 12:43793723-43806375 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000395510 TWF1-001 43793723-43806375 protein_coding
  ENST00000546506 TWF1-006 43800474-43806316 protein_coding
  ENST00000546662 TWF1-007 43797302-43806296 protein_coding
  ENST00000547459 TWF1-004 43793725-43806262 nonsense_mediated_decay
  ENST00000547564 TWF1-010 43802284-43806282 processed_transcript
  ENST00000547961 TWF1-011 43804153-43806255 retained_intron
  ENST00000548315 TWF1-005 43795493-43806249 protein_coding
  ENST00000548403 TWF1-012 43799462-43806300 protein_coding
  ENST00000550371 TWF1-008 43799417-43806328 nonsense_mediated_decay
  ENST00000551789 TWF1-009 43795556-43797851 retained_intron
  ENST00000552521 TWF1-003 43793723-43806287 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000395510ENST00000552521
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000395510 2.336±0.62 15.566±10.48 N/A 34.705±0.00 19.394±17.44
ENST00000552521 5.807±2.50 4.160±1.20 13.766±0.00 N/A 3.086±3.26

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0006R5 CIL_0006R5_0001 CGP
CIL_0006R8 CIL_0006R8_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003779 IEA actin binding
GO:0003785 ISS actin monomer binding
GO:0004713 IEA protein tyrosine kinase activity
GO:0005524 IDA ATP binding
GO:0005546 ISS phosphatidylinositol-4,5-bisphosphate binding
GO:0005622 IEA intracellular
GO:0005737 IDA cytoplasm
GO:0005911 ISS cell-cell junction
GO:0005925 IDA focal adhesion
GO:0015629 ISS actin cytoskeleton
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0030016 ISS myofibril
GO:0030175 ISS filopodium
GO:0030837 ISS negative regulation of actin filament polymerization
GO:0032587 ISS ruffle membrane
GO:0042989 ISS sequestering of actin monomers
GO:0043538 IDA regulation of actin phosphorylation
GO:0048471 ISS perinuclear region of cytoplasm
GO:0051016 IEA barbed-end actin filament capping

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011661 twf1b protein_coding Danio_rerio
ENSMUSG00000022451 Twf1 protein_coding Mus_musculus

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