ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: twinfilin actin-binding protein 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000395510 TWF1-001 ENSG00000151239 9606 - 12:43793723-43806375 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000395510
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000395510 2.336±0.62 15.566±10.48 34.705±0.00 19.394±17.44

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003779 IEA actin binding
GO:0003785 ISS actin monomer binding
GO:0005524 IDA ATP binding
GO:0005546 ISS phosphatidylinositol-4,5-bisphosphate binding
GO:0005622 IEA intracellular
GO:0005737 IDA cytoplasm
GO:0005911 ISS cell-cell junction
GO:0005925 IDA focal adhesion
GO:0015629 ISS actin cytoskeleton
GO:0030016 ISS myofibril
GO:0030175 ISS filopodium
GO:0030837 ISS negative regulation of actin filament polymerization
GO:0032587 ISS ruffle membrane
GO:0042989 ISS sequestering of actin monomers
GO:0043538 IDA regulation of actin phosphorylation
GO:0048471 ISS perinuclear region of cytoplasm

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000023087 Twf1-001 protein_coding Mus_musculus 0 1657
ENSMUST00000122230 Gm4887-001 processed_pseudogene Mus_musculus 0 1264
ENSMUST00000155654 Twf1-003 processed_transcript Mus_musculus 0 641
ENSMUST00000152590 Twf1-002 protein_coding Mus_musculus 0 409
ENSMUST00000127347 Twf1-004 retained_intron Mus_musculus 0 289
ENSMUST00000109248 Irak4-002 protein_coding Mus_musculus 0 220

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