ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000152952 PLOD2 9606 - 3:146069440-146163653 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000282903 PLOD2-001 146069440-146161167 protein_coding
  ENST00000360060 PLOD2-002 146069444-146161167 protein_coding
  ENST00000460520 PLOD2-008 146081791-146088815 retained_intron
  ENST00000461497 PLOD2-005 146069440-146085889 protein_coding
  ENST00000469350 PLOD2-006 146102760-146163653 protein_coding
  ENST00000475505 PLOD2-009 146072557-146073657 retained_intron
  ENST00000478436 PLOD2-004 146075925-146086735 retained_intron
  ENST00000480704 PLOD2-007 146110300-146160991 nonsense_mediated_decay
  ENST00000494950 PLOD2-003 146070181-146160992 protein_coding
  ENST00000495700 PLOD2-010 146070241-146071170 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHMVEC-DHUVECENST00000282903ENST00000360060ENST00000469350ENST00000478436ENST00000480704ENST00000494950
Transcript ID HAoEC HMVEC-D HUVEC
ENST00000282903 24.631±22.53 121.864±0.00 83.961±101.73
ENST00000360060 7.938±1.20 N/A 16.526±14.86
ENST00000469350 N/A N/A 30.700±4.23
ENST00000478436 N/A N/A 7.496±0.00
ENST00000480704 N/A N/A 64.236±4.26
ENST00000494950 10.277±4.72 31.153±0.00 9.794±1.70

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001666 IEP response to hypoxia
GO:0005506 IEA iron ion binding
GO:0005581 IEA collagen trimer
GO:0005783 IEA:TAS endoplasmic reticulum
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006464 TAS cellular protein modification process
GO:0008475 IEA procollagen-lysine 5-dioxygenase activity
GO:0016491 IEA oxidoreductase activity
GO:0016705 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016706 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0030198 TAS extracellular matrix organization
GO:0031418 IEA L-ascorbic acid binding
GO:0055114 IEA oxidation-reduction process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011821 plod2 protein_coding Danio_rerio
ENSMUSG00000032374 Plod2 protein_coding Mus_musculus

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