ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: sodium channel, voltage-gated, type III, alpha subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000153253 SCN3A 9606 - 2:165087522-165204067 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000283254 SCN3A-001 165087530-165204043 protein_coding
  ENST00000360093 SCN3A-201 165087522-165204067 protein_coding
  ENST00000409101 SCN3A-002 165089718-165203886 protein_coding
  ENST00000440431 SCN3A-004 165097252-165186554 protein_coding
  ENST00000453007 SCN3A-003 165164393-165204050 protein_coding
  ENST00000465043 SCN3A-007 165092256-165093828 processed_transcript
  ENST00000471697 SCN3A-006 165095511-165097614 retained_intron
  ENST00000484898 SCN3A-008 165122800-165127792 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHUVECENST00000283254ENST00000360093ENST00000440431ENST00000453007
Transcript ID BECs HAoEC HHSEC HUVEC
ENST00000283254 0.012±0.00 N/A 0.006±0.00 0.002±0.00
ENST00000360093 0.011±0.00 N/A 0.006±0.00 0.002±0.00
ENST00000440431 0.016±0.00 N/A N/A 0.006±0.00
ENST00000453007 0.095±0.05 0.033±0.00 N/A 0.022±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0006CP CIL_0006CP_0001 CGP
CIL_0006CO CIL_0006CO_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001518 IEA voltage-gated sodium channel complex
GO:0005216 IEA ion channel activity
GO:0005248 IEA:NAS voltage-gated sodium channel activity
GO:0005515 IEA protein binding
GO:0005737 IEA cytoplasm
GO:0005886 IBA plasma membrane
GO:0006811 IEA ion transport
GO:0006814 NAS:IEA sodium ion transport
GO:0016020 IEA membrane
GO:0019228 IBA neuronal action potential
GO:0034765 IEA regulation of ion transmembrane transport
GO:0035725 IEA sodium ion transmembrane transport
GO:0055085 IEA transmembrane transport
GO:0086010 IBA membrane depolarization during action potential

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062744 scn1lab protein_coding Danio_rerio
ENSMUSG00000057182 Scn3a protein_coding Mus_musculus

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