ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: TRAF2 and NCK interacting kinase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000154310 TNIK 9606 - 3:171061339-171460408 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000284483 TNIK-004 171063881-171460063 protein_coding
  ENST00000341852 TNIK-003 171063330-171460408 protein_coding
  ENST00000357327 TNIK-006 171063881-171460063 protein_coding
  ENST00000436636 TNIK-001 171061339-171460408 protein_coding
  ENST00000459881 TNIK-017 171066487-171071406 retained_intron
  ENST00000460047 TNIK-007 171063881-171460063 protein_coding
  ENST00000464785 TNIK-016 171063552-171064042 processed_transcript
  ENST00000465393 TNIK-002 171346934-171460405 protein_coding
  ENST00000468757 TNIK-012 171157551-171225711 protein_coding
  ENST00000470834 TNIK-009 171063881-171460063 protein_coding
  ENST00000475336 TNIK-005 171063881-171460063 protein_coding
  ENST00000484051 TNIK-011 171066374-171082682 retained_intron
  ENST00000487846 TNIK-015 171066470-171079583 retained_intron
  ENST00000488470 TNIK-008 171063881-171460063 protein_coding
  ENST00000496492 TNIK-010 171063261-171102072 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000341852ENST00000436636ENST00000465393ENST00000470834ENST00000475336
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000341852 N/A 2.518±0.12 0.804±0.00 3.189±0.90
ENST00000436636 N/A 4.390±1.96 N/A 5.191±3.60
ENST00000465393 4.408±1.17 N/A N/A 3.515±0.00
ENST00000470834 N/A 7.690±3.42 1.770±0.00 3.714±2.47
ENST00000475336 N/A N/A N/A 1.460±0.36

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0008FL CIL_0008FL_0001 VISTA
CIL_00080K CIL_00080K_0001 VISTA
CIL_0007SJ CIL_0007SJ_0001 VISTA
CIL_00049S CIL_00049S_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005083 IEA small GTPase regulator activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005768 IEA endosome
GO:0005856 IDA cytoskeleton
GO:0006468 IEA protein phosphorylation
GO:0007010 IMP cytoskeleton organization
GO:0007256 IMP activation of JNKK activity
GO:0016055 IEA Wnt signaling pathway
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0031532 IDA actin cytoskeleton reorganization
GO:0035556 IDA intracellular signal transduction
GO:0046777 IDA protein autophosphorylation
GO:0048814 IDA regulation of dendrite morphogenesis
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000009031 tnikb protein_coding Danio_rerio
ENSDARG00000056218 tnika protein_coding Danio_rerio
ENSMUSG00000027692 Tnik protein_coding Mus_musculus

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