ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000027692 Tnik 10090 + 3:28263214-28675858 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000159236 Tnik-001 28263215-28675858 protein_coding
  ENSMUST00000159308 Tnik-011 28263643-28667982 protein_coding
  ENSMUST00000159680 Tnik-010 28263563-28668223 protein_coding
  ENSMUST00000159733 Tnik-006 28650027-28665945 retained_intron
  ENSMUST00000160307 Tnik-007 28263563-28668223 protein_coding
  ENSMUST00000160518 Tnik-008 28263643-28667982 protein_coding
  ENSMUST00000160934 Tnik-003 28263214-28670585 nonsense_mediated_decay
  ENSMUST00000161214 Tnik-005 28263276-28360786 retained_intron
  ENSMUST00000161234 Tnik-002 28263276-28494134 retained_intron
  ENSMUST00000161423 Tnik-004 28409431-28596083 processed_transcript
  ENSMUST00000161964 Tnik-014 28263643-28667982 protein_coding
  ENSMUST00000162037 Tnik-016 28263563-28666449 retained_intron
  ENSMUST00000162225 Tnik-015 28629872-28638469 retained_intron
  ENSMUST00000162485 Tnik-009 28263643-28667982 protein_coding
  ENSMUST00000162777 Tnik-013 28263643-28667982 protein_coding
  ENSMUST00000192205 Tnik-019 28666846-28668749 retained_intron
  ENSMUST00000193721 Tnik-017 28538278-28540092 retained_intron
  ENSMUST00000195094 Tnik-018 28263582-28264866 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000159236ENSMUST00000160518ENSMUST00000160934ENSMUST00000161214ENSMUST00000161423ENSMUST00000161964ENSMUST00000195094
Transcript ID C166 Tie2+ EC mES
ENSMUST00000159236 N/A 0.072±0.00 0.134±0.00
ENSMUST00000160518 0.889±0.00 N/A N/A
ENSMUST00000160934 2.080±0.84 0.434±0.13 0.644±0.34
ENSMUST00000161214 N/A 0.784±0.00 N/A
ENSMUST00000161423 N/A 0.912±0.00 2.077±1.37
ENSMUST00000161964 0.943±0.00 N/A N/A
ENSMUST00000195094 N/A 0.357±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00070U CIL_00070U_0002 CGP
CIL_0007SJ CIL_0007SJ_0002 VISTA
CIL_00080K CIL_00080K_0002 VISTA
CIL_0008FL CIL_0008FL_0002 VISTA
CIL_000710 CIL_000710_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004674 ISS protein serine/threonine kinase activity
GO:0005083 IEA small GTPase regulator activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 ISS cytoplasm
GO:0005856 ISS cytoskeleton
GO:0006468 ISS protein phosphorylation
GO:0007010 IEA cytoskeleton organization
GO:0007256 ISS activation of JNKK activity
GO:0016055 IEA Wnt signaling pathway
GO:0031532 ISS actin cytoskeleton reorganization
GO:0035556 ISS intracellular signal transduction
GO:0046777 ISS protein autophosphorylation
GO:0048471 ISO perinuclear region of cytoplasm
GO:0048814 ISS regulation of dendrite morphogenesis
GO:0050790 IEA regulation of catalytic activity
GO:0055037 ISO recycling endosome
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000009031 tnikb protein_coding Danio_rerio
ENSDARG00000056218 tnika protein_coding Danio_rerio
ENSG00000154310 TNIK TRAF2 and NCK interacting kinase protein_coding Homo_sapiens

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