ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: TSEN2 tRNA splicing endonuclease subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000154743 TSEN2 9606 + 3:12484432-12539623 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000284995 TSEN2-001 12484511-12533317 protein_coding
  ENST00000402228 TSEN2-002 12484491-12533317 protein_coding
  ENST00000412698 TSEN2-008 12529871-12539620 protein_coding
  ENST00000415684 TSEN2-006 12489780-12533659 protein_coding
  ENST00000444864 TSEN2-201 12484511-12531013 protein_coding
  ENST00000446004 TSEN2-004 12484432-12528924 protein_coding
  ENST00000454502 TSEN2-003 12484443-12533317 protein_coding
  ENST00000455118 TSEN2-007 12529779-12539288 nonsense_mediated_decay
  ENST00000473755 TSEN2-005 12484511-12539623 retained_intron
  ENST00000475595 TSEN2-009 12530848-12533307 processed_transcript
  ENST00000490981 TSEN2-010 12503446-12505574 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000284995ENST00000402228ENST00000412698ENST00000415684ENST00000444864ENST00000446004ENST00000454502ENST00000473755ENST00000475595
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000284995 N/A N/A N/A N/A 0.377±0.14
ENST00000402228 N/A 1.667±1.14 N/A N/A 0.912±0.50
ENST00000412698 4.601±1.40 N/A 3.731±0.00 N/A 1.644±0.51
ENST00000415684 N/A 1.207±0.60 0.842±0.00 N/A 0.571±0.23
ENST00000444864 N/A N/A N/A N/A 0.319±0.00
ENST00000446004 N/A 2.165±0.77 N/A 2.795±0.00 1.204±0.34
ENST00000454502 N/A 1.144±0.26 N/A 1.627±0.00 1.172±0.35
ENST00000473755 N/A 0.489±0.20 0.368±0.00 N/A 0.457±0.46
ENST00000475595 2.569±1.33 2.823±0.45 3.296±0.00 N/A 1.640±0.57

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0004K9 CIL_0004K9_0001 CGP
CIL_0005SH CIL_0005SH_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000213 IEA tRNA-intron endonuclease activity
GO:0000214 IEA tRNA-intron endonuclease complex
GO:0003676 IEA nucleic acid binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005813 IDA centrosome
GO:0006388 IEA:IDA tRNA splicing, via endonucleolytic cleavage and ligation
GO:0006397 IEA mRNA processing
GO:0016829 IEA lyase activity
GO:0090502 IEA RNA phosphodiester bond hydrolysis, endonucleolytic

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000091851 tsen2 protein_coding Danio_rerio
ENSMUSG00000042389 Tsen2 protein_coding Mus_musculus

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