ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: FYVE, RhoGEF and PH domain containing 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000154783 FGD5 9606 + 3:14818962-14934565 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000285046 FGD5-001 14818962-14934388 protein_coding
  ENST00000457774 FGD5-005 14821432-14900453 protein_coding
  ENST00000468662 FGD5-002 14882305-14933438 processed_transcript
  ENST00000476851 FGD5-003 14896962-14933439 processed_transcript
  ENST00000487605 FGD5-004 14930763-14933438 retained_intron
  ENST00000543601 FGD5-201 14818962-14934565 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000285046ENST00000468662ENST00000543601
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000285046 6.388±0.00 13.600±5.79 11.099±0.00 13.922±5.19
ENST00000468662 15.483±0.00 N/A N/A N/A
ENST00000543601 N/A 16.767±7.79 N/A 13.679±6.15

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0007GJ CIL_0007GJ_0001 CGP
CIL_0005AG CIL_0005AG_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001726 ISS ruffle
GO:0005085 ISS guanyl-nucleotide exchange factor activity
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IPI protein binding
GO:0005737 ISS cytoplasm
GO:0005768 IEA endosome
GO:0005783 IEA endoplasmic reticulum
GO:0005794 ISS Golgi apparatus
GO:0005856 IEA cytoskeleton
GO:0005886 IEA plasma membrane
GO:0007010 ISS cytoskeleton organization
GO:0008360 ISS regulation of cell shape
GO:0030027 ISS lamellipodium
GO:0030036 ISS actin cytoskeleton organization
GO:0031267 ISS small GTPase binding
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0043088 ISS regulation of Cdc42 GTPase activity
GO:0043547 ISS positive regulation of GTPase activity
GO:0046847 ISS filopodium assembly
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000089622 fgd5b protein_coding Danio_rerio
ENSMUSG00000034037 Fgd5 protein_coding Mus_musculus

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