ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: folliculin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000154803 FLCN 9606 - 17:17212212-17237188 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000285071 FLCN-001 17212212-17237139 protein_coding
  ENST00000389168 FLCN-004 17224553-17229477 retained_intron
  ENST00000389169 FLCN-002 17221171-17237139 protein_coding
  ENST00000389171 FLCN-003 17224553-17237188 retained_intron
  ENST00000417064 FLCN-006 17223922-17237182 protein_coding
  ENST00000461699 FLCN-008 17228026-17228729 protein_coding
  ENST00000466317 FLCN-005 17219567-17223122 retained_intron
  ENST00000473853 FLCN-007 17231524-17232812 retained_intron
  ENST00000480316 FLCN-009 17221588-17224505 retained_intron
  ENST00000577591 FLCN-010 17216972-17219103 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHUVECENST00000285071
Transcript ID BECs HAoEC HUVEC
ENST00000285071 10.932±0.00 6.736±0.32 15.144±4.71

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0000NS CIL_0000NS_0001 CGP
CIL_0000NR CIL_0000NR_0001 CGP
CIL_00040N CIL_00040N_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0001701 ISS in utero embryonic development
GO:0001932 IDA regulation of protein phosphorylation
GO:0001934 ISS positive regulation of protein phosphorylation
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005886 IDA plasma membrane
GO:0007043 ISS cell-cell junction assembly
GO:0010629 ISS negative regulation of gene expression
GO:0010823 ISS negative regulation of mitochondrion organization
GO:0030097 ISS hemopoiesis
GO:0030308 IDA negative regulation of cell growth
GO:0030336 IMP negative regulation of cell migration
GO:0030496 IDA midbody
GO:0030511 ISS positive regulation of transforming growth factor beta receptor signaling pathway
GO:0031929 IMP TOR signaling
GO:0032006 ISS regulation of TOR signaling
GO:0032007 ISS negative regulation of TOR signaling
GO:0032008 ISS positive regulation of TOR signaling
GO:0032403 IDA protein complex binding
GO:0032465 IMP regulation of cytokinesis
GO:0035024 IMP negative regulation of Rho protein signal transduction
GO:0035065 ISS regulation of histone acetylation
GO:0043065 ISS positive regulation of apoptotic process
GO:0044291 IDA cell-cell contact zone
GO:0045785 IMP positive regulation of cell adhesion
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0051898 ISS negative regulation of protein kinase B signaling
GO:0070373 ISS negative regulation of ERK1 and ERK2 cascade
GO:1900181 IDA negative regulation of protein localization to nucleus
GO:1901723 ISS negative regulation of cell proliferation involved in kidney development
GO:2000506 ISS negative regulation of energy homeostasis
GO:2000973 ISS regulation of pro-B cell differentiation
GO:2001170 ISS negative regulation of ATP biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062385 flcn protein_coding Danio_rerio
ENSMUSG00000032633 Flcn protein_coding Mus_musculus

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