ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: calcium channel, voltage-dependent, L type, alpha 1D subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000157388 CACNA1D 9606 + 3:53494656-53813733 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000288139 CACNA1D-001 53495049-53813733 protein_coding
  ENST00000350061 CACNA1D-003 53494656-53812045 protein_coding
  ENST00000422281 CACNA1D-002 53495167-53811406 protein_coding
  ENST00000464429 CACNA1D-006 53666378-53674047 retained_intron
  ENST00000481085 CACNA1D-007 53666363-53722458 protein_coding
  ENST00000481478 CACNA1D-004 53666401-53811508 protein_coding
  ENST00000498251 CACNA1D-005 53673061-53679763 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000288139ENST00000350061ENST00000422281ENST00000481478ENST00000498251
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000288139 N/A N/A N/A N/A 0.003±0.00
ENST00000350061 N/A 0.030±0.01 N/A N/A 0.017±0.01
ENST00000422281 N/A 0.087±0.01 N/A N/A 0.011±0.00
ENST00000481478 N/A 0.017±0.01 N/A N/A 0.013±0.01
ENST00000498251 1.275±0.72 0.175±0.11 1.899±0.00 0.386±0.00 0.204±0.12

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005216 IEA ion channel activity
GO:0005245 IDA voltage-gated calcium channel activity
GO:0005515 IEA protein binding
GO:0005886 ISS plasma membrane
GO:0005891 IDA voltage-gated calcium channel complex
GO:0006112 TAS energy reserve metabolic process
GO:0006811 IEA ion transport
GO:0006816 IDA calcium ion transport
GO:0007188 ISS adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007411 TAS axon guidance
GO:0007605 IMP sensory perception of sound
GO:0008331 IDA high voltage-gated calcium channel activity
GO:0016020 IEA membrane
GO:0030018 ISS Z disc
GO:0030506 ISS ankyrin binding
GO:0034765 IEA regulation of ion transmembrane transport
GO:0044281 TAS small molecule metabolic process
GO:0046872 IEA metal ion binding
GO:0050796 TAS regulation of insulin secretion
GO:0051393 IPI alpha-actinin binding
GO:0051928 IDA positive regulation of calcium ion transport
GO:0055085 IEA transmembrane transport
GO:0060372 ISS regulation of atrial cardiac muscle cell membrane repolarization
GO:0070509 IDA calcium ion import
GO:0070588 ISS calcium ion transmembrane transport
GO:0086007 IC voltage-gated calcium channel activity involved in cardiac muscle cell action potential
GO:0086010 IBA membrane depolarization during action potential
GO:0086012 IC membrane depolarization during cardiac muscle cell action potential
GO:0086046 IEA membrane depolarization during SA node cell action potential
GO:0086052 IMP membrane repolarization during SA node cell action potential
GO:0086059 IMP voltage-gated calcium channel activity involved SA node cell action potential
GO:0086091 IMP regulation of heart rate by cardiac conduction
GO:1901016 ISS regulation of potassium ion transmembrane transporter activity
GO:1901379 ISS regulation of potassium ion transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000015968 Cacna1d protein_coding Mus_musculus

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