ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: calcium channel, voltage-dependent, L type, alpha 1D subunit
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000422281 CACNA1D-002 ENSG00000157388 9606 + 3:53495167-53811406 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHUVECENST00000422281
Transcript ID HAoEC HUVEC
ENST00000422281 0.087±0.01 0.011±0.00

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005216 IEA ion channel activity
GO:0005245 IDA voltage-gated calcium channel activity
GO:0005886 ISS plasma membrane
GO:0005891 IDA voltage-gated calcium channel complex
GO:0006112 TAS energy reserve metabolic process
GO:0006811 IEA ion transport
GO:0006816 IDA calcium ion transport
GO:0007188 ISS adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007411 TAS axon guidance
GO:0007605 IMP sensory perception of sound
GO:0008331 IDA high voltage-gated calcium channel activity
GO:0016020 IEA membrane
GO:0030018 ISS Z disc
GO:0030506 ISS ankyrin binding
GO:0044281 TAS small molecule metabolic process
GO:0046872 IEA metal ion binding
GO:0050796 TAS regulation of insulin secretion
GO:0051393 IPI alpha-actinin binding
GO:0051928 IDA positive regulation of calcium ion transport
GO:0055085 IEA transmembrane transport
GO:0060372 ISS regulation of atrial cardiac muscle cell membrane repolarization
GO:0070509 IDA calcium ion import
GO:0070588 ISS calcium ion transmembrane transport
GO:0086007 IC voltage-gated calcium channel activity involved in cardiac muscle cell action potential
GO:0086010 IBA membrane depolarization during action potential
GO:0086012 IC membrane depolarization during cardiac muscle cell action potential
GO:0086052 IMP membrane repolarization during SA node cell action potential
GO:0086059 IMP voltage-gated calcium channel activity involved SA node cell action potential
GO:0086091 IMP regulation of heart rate by cardiac conduction
GO:1901016 ISS regulation of potassium ion transmembrane transporter activity
GO:1901379 ISS regulation of potassium ion transmembrane transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000112249 Cacna1d-201 protein_coding Mus_musculus 0 7461
ENSMUST00000112250 Cacna1d-202 protein_coding Mus_musculus 0 7361
ENSMUST00000188106 Cacna1c-011 protein_coding Mus_musculus 0 1188
ENSMUST00000115725 Cacna1f-002 protein_coding Mus_musculus 0 1182
ENSMUST00000161865 Cacna1s-003 protein_coding Mus_musculus 0 1168
ENSMUST00000112068 Cacna1s-001 protein_coding Mus_musculus 0 1168
ENSMUST00000115726 Cacna1f-001 protein_coding Mus_musculus 0 1131
ENSMUST00000155090 Cacna1f-003 nonsense_mediated_decay Mus_musculus 0 1131
ENSMUST00000112825 Cacna1c-201 protein_coding Mus_musculus 0 1131
ENSMUST00000188181 Cacna1c-012 processed_transcript Mus_musculus 0 1131
ENSMUST00000141634 Cacna1f-004 retained_intron Mus_musculus 0 1094
ENSMUST00000187474 Cacna1c-008 protein_coding Mus_musculus 0 939
ENSMUST00000187940 Cacna1c-002 protein_coding Mus_musculus 0 939
ENSMUST00000112790 Cacna1c-005 protein_coding Mus_musculus 0 939
ENSMUST00000075591 Cacna1c-024 protein_coding Mus_musculus 0 939
ENSMUST00000078320 Cacna1c-004 protein_coding Mus_musculus 0 939
ENSMUST00000186889 Cacna1c-001 protein_coding Mus_musculus 0 939
ENSDART00000028856 cacna1c-201 protein_coding Danio_rerio 0 894
ENSDART00000132909 cacna1c-001 protein_coding Danio_rerio 0 894
ENSMUST00000188865 Cacna1c-020 protein_coding Mus_musculus 0 861
ENSMUST00000185345 Cacna1c-019 protein_coding Mus_musculus 0 861
ENSMUST00000187317 Cacna1c-018 protein_coding Mus_musculus 0 861
ENSMUST00000189520 Cacna1c-017 protein_coding Mus_musculus 0 861
ENSMUST00000189389 Cacna1c-016 protein_coding Mus_musculus 0 861
ENSMUST00000188078 Cacna1c-015 protein_coding Mus_musculus 0 861
ENSMUST00000112064 Cacna1s-201 protein_coding Mus_musculus 0 597
ENSMUST00000160641 Cacna1s-002 protein_coding Mus_musculus 0 597
ENSMUST00000190285 Cacna1c-007 protein_coding Mus_musculus 0 580
ENSMUST00000112793 Cacna1c-010 protein_coding Mus_musculus 0 555
ENSMUST00000187386 Cacna1c-006 protein_coding Mus_musculus 0 555
ENSMUST00000188522 Cacna1c-014 protein_coding Mus_musculus 0 555
ENSDART00000105895 cacna1sa-001 protein_coding Danio_rerio 0 525
ENSMUST00000189057 Cacna1c-003 processed_transcript Mus_musculus 1e-19 104
ENSDART00000089967 cacna1bb-201 protein_coding Danio_rerio 4e-19 102
ENSDART00000013228 cacna1aa-201 protein_coding Danio_rerio 0.0000000000005 82
ENSDART00000138765 cacna1aa-002 protein_coding Danio_rerio 0.0000000000005 82
ENSDART00000144774 cacna1aa-001 protein_coding Danio_rerio 0.0000000000005 82

Loading