ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: SKI proto-oncogene
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000157933 SKI 9606 + 1:2228695-2310119 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000378536 SKI-001 2228695-2310119 protein_coding
  ENST00000478223 SKI-002 2247996-2303376 processed_transcript
  ENST00000507179 SKI-005 2303646-2304368 retained_intron
  ENST00000508416 SKI-004 2232479-2303038 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000378536
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000378536 0.941±0.00 24.684±12.16 16.116±0.00 9.917±8.67

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0007QV CIL_0007QV_0001 VISTA

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0001843 ISS neural tube closure
GO:0002089 ISS lens morphogenesis in camera-type eye
GO:0003682 IEA chromatin binding
GO:0003714 IMP transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005667 ISS transcription factor complex
GO:0005737 ISS cytoplasm
GO:0005813 IDA centrosome
GO:0006351 TAS transcription, DNA-templated
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0007179 NAS transforming growth factor beta receptor signaling pathway
GO:0008270 IDA zinc ion binding
GO:0008283 NAS cell proliferation
GO:0008285 IDA negative regulation of cell proliferation
GO:0009948 ISS anterior/posterior axis specification
GO:0010467 TAS gene expression
GO:0010626 IGI negative regulation of Schwann cell proliferation
GO:0014902 IDA myotube differentiation
GO:0016604 IDA nuclear body
GO:0016605 IDA PML body
GO:0017053 ISS transcriptional repressor complex
GO:0019901 IPI protein kinase binding
GO:0019904 IPI protein domain specific binding
GO:0021772 ISS olfactory bulb development
GO:0022011 ISS myelination in peripheral nervous system
GO:0030177 NAS positive regulation of Wnt signaling pathway
GO:0030326 ISS embryonic limb morphogenesis
GO:0030509 TAS BMP signaling pathway
GO:0030512 IGI negative regulation of transforming growth factor beta receptor signaling pathway
GO:0030514 IDA negative regulation of BMP signaling pathway
GO:0031064 IEA negative regulation of histone deacetylation
GO:0031625 IPI ubiquitin protein ligase binding
GO:0032926 IDA negative regulation of activin receptor signaling pathway
GO:0035019 ISS somatic stem cell maintenance
GO:0042981 IBA regulation of apoptotic process
GO:0043010 ISS camera-type eye development
GO:0043234 IDA protein complex
GO:0043388 IDA positive regulation of DNA binding
GO:0043585 ISS nose morphogenesis
GO:0045668 IDA negative regulation of osteoblast differentiation
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0046332 IPI:IEA SMAD binding
GO:0046811 ISS histone deacetylase inhibitor activity
GO:0048147 ISS negative regulation of fibroblast proliferation
GO:0048593 ISS camera-type eye morphogenesis
GO:0048741 ISS skeletal muscle fiber development
GO:0048870 NAS cell motility
GO:0060021 ISS palate development
GO:0060041 ISS retina development in camera-type eye
GO:0060325 ISS face morphogenesis
GO:0060349 ISS bone morphogenesis
GO:0060395 IDA SMAD protein signal transduction
GO:0070207 IDA protein homotrimerization
GO:0070491 IPI repressing transcription factor binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000008034 skib protein_coding Danio_rerio
ENSDARG00000042151 skia protein_coding Danio_rerio
ENSMUSG00000029050 Ski protein_coding Mus_musculus

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