ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: death effector domain containing 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000160570 DEDD2 9606 - 19:42198598-42220140 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000336034 DEDD2-011 42198598-42217669 protein_coding
  ENST00000593561 DEDD2-004 42201855-42220140 processed_transcript
  ENST00000593804 DEDD2-002 42198616-42217742 processed_transcript
  ENST00000595337 DEDD2-001 42198613-42220123 protein_coding
  ENST00000596251 DEDD2-003 42199359-42217716 protein_coding
  ENST00000598090 DEDD2-007 42199793-42217712 processed_transcript
  ENST00000598200 DEDD2-013 42215228-42217681 protein_coding
  ENST00000598415 DEDD2-006 42199567-42217724 processed_transcript
  ENST00000598727 DEDD2-010 42201714-42217682 protein_coding
  ENST00000600559 DEDD2-012 42199603-42217708 processed_transcript
  ENST00000601135 DEDD2-008 42199465-42217706 processed_transcript
  ENST00000602075 DEDD2-009 42199594-42217701 processed_transcript
  ENST00000602201 DEDD2-005 42201904-42217757 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000336034ENST00000593804ENST00000595337ENST00000596251ENST00000598200
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000336034 5.927±0.00 3.402±1.51 N/A 2.534±0.00 3.727±2.24
ENST00000593804 8.686±5.45 2.596±1.72 N/A N/A 5.034±4.58
ENST00000595337 3.130±0.00 0.364±0.00 1.512±0.00 N/A 2.251±0.83
ENST00000596251 N/A 1.076±0.35 N/A N/A 3.279±0.00
ENST00000598200 N/A 10.856±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0003X4 CIL_0003X4_0001 CGP
CIL_00028B CIL_00028B_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0005515 IEA protein binding
GO:0005730 IDA nucleolus
GO:0006351 IEA transcription, DNA-templated
GO:0006396 NAS RNA processing
GO:0008625 IMP extrinsic apoptotic signaling pathway via death domain receptors
GO:0016075 NAS rRNA catabolic process
GO:0019725 NAS cellular homeostasis
GO:0030159 NAS receptor signaling complex scaffold activity
GO:0030262 IDA apoptotic nuclear changes
GO:0035556 NAS intracellular signal transduction
GO:0042981 IEA regulation of apoptotic process
GO:0045892 NAS negative regulation of transcription, DNA-templated
GO:2001238 IMP positive regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000002758 dedd1 protein_coding Danio_rerio
ENSDARG00000093482 dedd1 protein_coding Danio_rerio
ENSMUSG00000054499 Dedd2 protein_coding Mus_musculus

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