ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: proprotein convertase subtilisin/kexin type 7
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000160613 PCSK7 9606 - 11:117204337-117232525 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000320934 PCSK7-001 117204337-117232525 protein_coding
  ENST00000524507 PCSK7-007 117229506-117231868 protein_coding
  ENST00000525027 PCSK7-004 117224700-117230240 protein_coding
  ENST00000527037 PCSK7-009 117206148-117220138 retained_intron
  ENST00000527861 PCSK7-013 117206680-117208681 retained_intron
  ENST00000528217 PCSK7-008 117219124-117223063 retained_intron
  ENST00000528973 PCSK7-011 117208673-117218464 retained_intron
  ENST00000529458 PCSK7-015 117205947-117208136 processed_transcript
  ENST00000530269 PCSK7-005 117229570-117232525 protein_coding
  ENST00000531573 PCSK7-014 117207693-117208488 retained_intron
  ENST00000532301 PCSK7-006 117229567-117232074 protein_coding
  ENST00000532810 PCSK7-012 117206774-117209365 retained_intron
  ENST00000533135 PCSK7-010 117207775-117219165 processed_transcript
  ENST00000534529 PCSK7-003 117205074-117226876 retained_intron
  ENST00000540028 PCSK7-201 117205078-117232095 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHHSECHUVECENST00000320934ENST00000525027ENST00000528973ENST00000534529ENST00000540028
Transcript ID HAoEC HHSEC HUVEC
ENST00000320934 1.171±0.00 16.542±0.00 4.079±3.17
ENST00000525027 4.172±0.40 N/A 11.867±1.42
ENST00000528973 0.964±0.09 N/A 1.707±1.02
ENST00000534529 N/A N/A 1.927±2.01
ENST00000540028 2.210±0.16 N/A 4.366±2.41

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0007RC CIL_0007RC_0001 VISTA

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004252 IEA:IBA serine-type endopeptidase activity
GO:0006508 IEA proteolysis
GO:0008233 IDA peptidase activity
GO:0016485 IDA protein processing
GO:0016486 NAS peptide hormone processing
GO:0030173 IDA integral component of Golgi membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000069968 pcsk7 protein_coding Danio_rerio
ENSMUSG00000035382 Pcsk7 protein_coding Mus_musculus

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