ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: dishevelled segment polarity protein 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000161202 DVL3 9606 + 3:184155388-184173610 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000313143 DVL3-001 184155388-184173610 protein_coding
  ENST00000423300 DVL3-005 184156775-184166509 protein_coding
  ENST00000431765 DVL3-002 184155560-184170873 protein_coding
  ENST00000435708 DVL3-006 184155558-184164517 nonsense_mediated_decay
  ENST00000462665 DVL3-007 184155562-184164912 processed_transcript
  ENST00000467873 DVL3-009 184164647-184165478 retained_intron
  ENST00000478247 DVL3-004 184163677-184170876 retained_intron
  ENST00000478639 DVL3-008 184166194-184166701 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000313143ENST00000431765ENST00000478247
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000313143 2.140±0.00 4.865±2.94 10.707±0.00 10.261±5.46
ENST00000431765 25.256±12.97 6.382±2.45 N/A 13.397±6.85
ENST00000478247 14.761±0.00 2.220±1.05 7.058±0.00 9.324±4.92

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0005G3 CIL_0005G3_0001 CGP
CIL_0003YF CIL_0003YF_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001934 IMP positive regulation of protein phosphorylation
GO:0002020 IPI protease binding
GO:0003007 IEA heart morphogenesis
GO:0003148 IBA outflow tract septum morphogenesis
GO:0005102 IPI receptor binding
GO:0005109 IPI frizzled binding
GO:0005515 IPI:IEA protein binding
GO:0005737 IEA cytoplasm
GO:0005938 IBA cell cortex
GO:0008013 IDA beta-catenin binding
GO:0016055 IDA Wnt signaling pathway
GO:0035556 IEA intracellular signal transduction
GO:0035567 IMP non-canonical Wnt signaling pathway
GO:0038031 ISS non-canonical Wnt signaling pathway via JNK cascade
GO:0042493 IEA response to drug
GO:0043507 IMP positive regulation of JUN kinase activity
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0046982 IDA protein heterodimerization activity
GO:0060026 IBA convergent extension
GO:0060070 IDA canonical Wnt signaling pathway
GO:0060071 IDA Wnt signaling pathway, planar cell polarity pathway
GO:0090103 IBA cochlea morphogenesis
GO:0090179 IBA planar cell polarity pathway involved in neural tube closure

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015707 dvl3a protein_coding Danio_rerio
ENSMUSG00000003233 Dvl3 protein_coding Mus_musculus

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