ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000003233 Dvl3 10090 + 16:20516982-20532520 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000003318 Dvl3-001 20516982-20531650 protein_coding
  ENSMUST00000169552 Dvl3-002 20517186-20525319 retained_intron
  ENSMUST00000171572 Dvl3-003 20517064-20532520 protein_coding
  ENSMUST00000171774 Dvl3-004 20517106-20531646 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000171572
Transcript ID C166 Tie2+ EC mES
ENSMUST00000171572 7.759±0.64 3.679±0.00 3.394±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0005G3 CIL_0005G3_0002 CGP
CIL_0003YF CIL_0003YF_0003 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001934 IEA positive regulation of protein phosphorylation
GO:0002020 IEA protease binding
GO:0003007 IGI heart morphogenesis
GO:0003148 IMP outflow tract septum morphogenesis
GO:0005102 IEA receptor binding
GO:0005109 IBA frizzled binding
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005938 IBA cell cortex
GO:0008013 IBA beta-catenin binding
GO:0016055 IEA Wnt signaling pathway
GO:0023051 IBA regulation of signaling
GO:0035556 IEA intracellular signal transduction
GO:0035567 IEA non-canonical Wnt signaling pathway
GO:0038031 IDA non-canonical Wnt signaling pathway via JNK cascade
GO:0042493 IEA response to drug
GO:0043507 IEA positive regulation of JUN kinase activity
GO:0045893 IBA positive regulation of transcription, DNA-templated
GO:0046982 IEA protein heterodimerization activity
GO:0060026 IBA convergent extension
GO:0060070 IBA canonical Wnt signaling pathway
GO:0060071 TAS Wnt signaling pathway, planar cell polarity pathway
GO:0090103 IGI cochlea morphogenesis
GO:0090179 IGI planar cell polarity pathway involved in neural tube closure

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015707 dvl3a protein_coding Danio_rerio
ENSG00000161202 DVL3 dishevelled segment polarity protein 3 protein_coding Homo_sapiens

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