ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: chemokine (C-X-C motif) ligand 16
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000161921 CXCL16 9606 - 17:4733526-4739922 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000293778 CXCL16-001 4733526-4739819 protein_coding
  ENST00000573123 CXCL16-004 4735367-4739145 protein_coding
  ENST00000574412 CXCL16-002 4734286-4739922 protein_coding
  ENST00000575168 CXCL16-005 4734583-4738539 retained_intron
  ENST00000576153 CXCL16-003 4733575-4736380 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000293778ENST00000574412ENST00000576153
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000293778 1.966±0.33 4.193±2.63 N/A 3.448±0.00 3.078±2.80
ENST00000574412 N/A 2.954±1.89 N/A N/A 3.390±1.20
ENST00000576153 N/A N/A 89.150±0.00 N/A 1.573±0.29

Conserved Regions

Region IDSub-RegionRegion Type
CIL_000106 CIL_000106_0001 CGP
CIL_0001RD CIL_0001RD_0001 CGP
CIL_0001RE CIL_0001RE_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005041 ISS low-density lipoprotein receptor activity
GO:0005044 TAS scavenger receptor activity
GO:0005576 TAS extracellular region
GO:0005615 IDA extracellular space
GO:0005886 IEA plasma membrane
GO:0006898 IEA:NAS receptor-mediated endocytosis
GO:0006935 NAS chemotaxis
GO:0008009 ISS chemokine activity
GO:0010818 IEA T cell chemotaxis
GO:0016020 TAS membrane
GO:0016021 NAS integral component of membrane
GO:0030307 IEA:IMP positive regulation of cell growth
GO:0030335 IEA:IMP positive regulation of cell migration
GO:0034097 IDA response to cytokine
GO:0034341 IEA:IDA response to interferon-gamma
GO:0034612 IEA:IDA response to tumor necrosis factor
GO:0048247 IEA lymphocyte chemotaxis
GO:0071222 IEA cellular response to lipopolysaccharide

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000018920 Cxcl16 protein_coding Mus_musculus

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