ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: amyloid beta (A4) precursor protein-binding, family B, member 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000163697 APBB2 9606 - 4:40810027-41216714 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000295974 APBB2-002 40810027-41214618 protein_coding
  ENST00000502682 APBB2-009 41065669-41216714 processed_transcript
  ENST00000502687 APBB2-031 40815973-40822466 retained_intron
  ENST00000502841 APBB2-007 40815333-40857155 protein_coding
  ENST00000503264 APBB2-019 41014288-41214518 protein_coding
  ENST00000503503 APBB2-016 41014388-41214485 protein_coding
  ENST00000503555 APBB2-011 41065590-41207908 processed_transcript
  ENST00000504305 APBB2-025 40815746-40857155 protein_coding
  ENST00000504484 APBB2-008 40892395-40935626 retained_intron
  ENST00000505266 APBB2-013 41193793-41214497 processed_transcript
  ENST00000506352 APBB2-012 40815617-41214615 protein_coding
  ENST00000506999 APBB2-015 41033290-41214569 processed_transcript
  ENST00000507831 APBB2-024 40823666-40890914 processed_transcript
  ENST00000508593 APBB2-003 40815324-41214532 protein_coding
  ENST00000508676 APBB2-010 41014336-41214608 protein_coding
  ENST00000508707 APBB2-018 41014213-41214520 protein_coding
  ENST00000509446 APBB2-020 41013947-41214493 protein_coding
  ENST00000509475 APBB2-004 40890309-41014385 retained_intron
  ENST00000510670 APBB2-026 40822030-40857192 protein_coding
  ENST00000510925 APBB2-030 40816085-40830515 nonsense_mediated_decay
  ENST00000511120 APBB2-022 40893363-40935440 retained_intron
  ENST00000511572 APBB2-017 41065605-41214569 processed_transcript
  ENST00000512510 APBB2-029 40821983-40890425 protein_coding
  ENST00000513140 APBB2-001 40814607-41214458 protein_coding
  ENST00000513493 APBB2-023 40825887-40893272 protein_coding
  ENST00000513516 APBB2-027 40823668-40857177 protein_coding
  ENST00000513611 APBB2-006 40815313-41014385 protein_coding
  ENST00000514094 APBB2-021 40826786-40934487 retained_intron
  ENST00000514920 APBB2-028 40823644-40842516 protein_coding
  ENST00000543538 APBB2-201 40810028-40857155 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000295974ENST00000502841ENST00000506352ENST00000508593ENST00000513140ENST00000513611ENST00000543538
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000295974 N/A 4.948±3.50 N/A 4.633±2.63
ENST00000502841 4.644±0.54 N/A N/A N/A
ENST00000506352 N/A N/A N/A 5.676±0.34
ENST00000508593 N/A 10.431±4.85 5.483±0.00 11.131±4.41
ENST00000513140 N/A 6.287±0.84 3.290±0.00 6.576±1.59
ENST00000513611 2.709±0.00 7.127±1.79 N/A 6.944±0.00
ENST00000543538 N/A 2.428±0.00 N/A 5.458±2.22

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00038T CIL_00038T_0001 CGP
CIL_00038S CIL_00038S_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001540 ISS beta-amyloid binding
GO:0001764 IEA neuron migration
GO:0005515 IPI:IEA protein binding
GO:0005634 ISS nucleus
GO:0005737 IEA cytoplasm
GO:0006355 ISS regulation of transcription, DNA-templated
GO:0007050 ISS cell cycle arrest
GO:0007411 IEA axon guidance
GO:0008134 ISS transcription factor binding
GO:0016020 NAS membrane
GO:0030027 ISS lamellipodium
GO:0030198 IEA extracellular matrix organization
GO:0030308 ISS negative regulation of cell growth
GO:0030426 ISS growth cone
GO:0035556 NAS intracellular signal transduction
GO:0043065 IEA positive regulation of apoptotic process
GO:0043066 IEA negative regulation of apoptotic process
GO:0045202 ISS synapse

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000029207 Apbb2 protein_coding Mus_musculus

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