ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: peptidylprolyl isomerase B (cyclophilin B)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000166794 PPIB 9606 - 15:64155812-64163205 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000300026 PPIB-001 64155812-64163205 protein_coding
  ENST00000558492 PPIB-003 64156778-64163006 processed_transcript
  ENST00000561048 PPIB-002 64159274-64163021 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000300026ENST00000558492
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000300026 1346.315±74.29 486.357±169.63 229.506±0.00 394.694±0.00 447.461±331.08
ENST00000558492 N/A N/A N/A N/A 273.977±155.60

Conserved Regions

Region IDSub-RegionRegion Type
CIL_000509 CIL_000509_0002 CGP
CIL_0002JZ CIL_0002JZ_0002 CGP

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000413 ISS:IEA protein peptidyl-prolyl isomerization
GO:0003755 ISS:IEA peptidyl-prolyl cis-trans isomerase activity
GO:0005515 IPI protein binding
GO:0005518 ISS collagen binding
GO:0005634 IDA nucleus
GO:0005783 IDA endoplasmic reticulum
GO:0005788 NAS endoplasmic reticulum lumen
GO:0005790 IEA smooth endoplasmic reticulum
GO:0005925 IDA focal adhesion
GO:0006457 IEA protein folding
GO:0016020 IDA membrane
GO:0030198 TAS extracellular matrix organization
GO:0032403 ISS protein complex binding
GO:0032991 ISS macromolecular complex
GO:0040018 IMP positive regulation of multicellular organism growth
GO:0042277 IEA peptide binding
GO:0044822 IDA poly(A) RNA binding
GO:0050821 IMP protein stabilization
GO:0051082 TAS unfolded protein binding
GO:0060348 IMP bone development
GO:0061077 IDA chaperone-mediated protein folding
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000092798 ppib protein_coding Danio_rerio
ENSMUSG00000032383 Ppib protein_coding Mus_musculus

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