ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: sodium channel, voltage-gated, type XI, alpha subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000168356 SCN11A 9606 - 3:38845769-38950561 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000302328 SCN11A-001 38845769-38950561 protein_coding
  ENST00000444237 SCN11A-002 38849278-38950561 protein_coding
  ENST00000456224 SCN11A-003 38846694-38950362 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000302328ENST00000444237ENST00000456224
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000302328 0.022±0.00 0.015±0.01 0.040±0.00 0.035±0.03
ENST00000444237 N/A 0.026±0.01 N/A 0.023±0.02
ENST00000456224 N/A 0.013±0.00 N/A 0.030±0.02

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0008BE CIL_0008BE_0001 VISTA
CIL_0004RE CIL_0004RE_0001 CGP
CIL_0006H1 CIL_0006H1_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001518 IEA voltage-gated sodium channel complex
GO:0005216 IEA ion channel activity
GO:0005248 IBA:IEA voltage-gated sodium channel activity
GO:0005515 IEA protein binding
GO:0005886 IBA plasma membrane
GO:0006811 IEA ion transport
GO:0006814 TAS:IEA sodium ion transport
GO:0008219 IEA cell death
GO:0016020 IEA membrane
GO:0019228 IBA neuronal action potential
GO:0030424 IEA axon
GO:0034765 IEA regulation of ion transmembrane transport
GO:0035725 IBA sodium ion transmembrane transport
GO:0042493 TAS response to drug
GO:0044299 IEA C-fiber
GO:0051930 ISS regulation of sensory perception of pain
GO:0055085 IEA transmembrane transport
GO:0070062 IDA extracellular vesicular exosome
GO:0086010 IBA membrane depolarization during action potential

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000034115 Scn11a protein_coding Mus_musculus

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