ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: APEX nuclease (apurinic/apyrimidinic endonuclease) 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000169188 APEX2 9606 + X:55000357-55009057 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000374987 APEX2-001 55000357-55009057 protein_coding
  ENST00000471758 APEX2-002 55000393-55006757 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000374987ENST00000471758
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000374987 4.867±0.00 9.170±3.09 0.793±0.00 5.859±0.00 10.208±8.81
ENST00000471758 N/A 7.910±1.97 N/A 4.946±0.00 4.169±0.75

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0000YC CIL_0000YC_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000737 IEA DNA catabolic process, endonucleolytic
GO:0000738 IBA DNA catabolic process, exonucleolytic
GO:0003677 IEA DNA binding
GO:0003906 IBA DNA-(apurinic or apyrimidinic site) lyase activity
GO:0004518 IEA nuclease activity
GO:0005634 IBA nucleus
GO:0005739 IEA mitochondrion
GO:0005743 IEA mitochondrial inner membrane
GO:0006281 IEA DNA repair
GO:0006284 IBA base-excision repair
GO:0006310 IEA DNA recombination
GO:0007049 IEA cell cycle
GO:0008270 IEA zinc ion binding
GO:0008311 IBA double-stranded DNA 3'-5' exodeoxyribonuclease activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000008472 apex2 protein_coding Danio_rerio
ENSMUSG00000025269 Apex2 protein_coding Mus_musculus

Loading