ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: APEX nuclease (apurinic/apyrimidinic endonuclease) 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000374987 APEX2-001 ENSG00000169188 9606 + X:55000357-55009057 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000374987
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000374987 4.867±0.00 9.170±3.09 0.793±0.00 5.859±0.00 10.208±8.81

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000737 IEA DNA catabolic process, endonucleolytic
GO:0000738 IBA DNA catabolic process, exonucleolytic
GO:0003677 IEA DNA binding
GO:0003906 IBA DNA-(apurinic or apyrimidinic site) lyase activity
GO:0004518 IEA nuclease activity
GO:0005634 IBA nucleus
GO:0005739 IEA mitochondrion
GO:0005743 IEA mitochondrial inner membrane
GO:0006281 IEA DNA repair
GO:0006284 IBA base-excision repair
GO:0006310 IEA DNA recombination
GO:0007049 IEA cell cycle
GO:0008270 IEA zinc ion binding
GO:0008311 IBA double-stranded DNA 3'-5' exodeoxyribonuclease activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000026303 Apex2-201 protein_coding Mus_musculus 0 1469
ENSMUST00000112720 Apex2-001 protein_coding Mus_musculus 0 1469
ENSMUST00000112721 Apex2-004 protein_coding Mus_musculus 0 1376
ENSMUST00000152332 Apex2-006 retained_intron Mus_musculus 0 1312
ENSMUST00000112719 Apex2-005 protein_coding Mus_musculus 0 767
ENSMUST00000112727 Apex2-003 protein_coding Mus_musculus 0 767
ENSMUST00000112725 Apex2-002 protein_coding Mus_musculus 0 767
ENSMUST00000140207 Apex2-009 protein_coding Mus_musculus 0 713
ENSMUST00000138958 Apex2-008 processed_transcript Mus_musculus 0 680
ENSMUST00000057256 6030458C11Rik-201 protein_coding Mus_musculus 0.0000004 62

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