ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: platelet-activating factor receptor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000169403 PTAFR 9606 - 1:28147166-28193936 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000305392 PTAFR-002 28149673-28193873 protein_coding
  ENST00000373857 PTAFR-001 28147166-28177188 protein_coding
  ENST00000539896 PTAFR-201 28147166-28193936 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000305392ENST00000373857ENST00000539896
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000305392 N/A 0.146±0.10 0.113±0.00 0.089±0.05
ENST00000373857 N/A 0.098±0.00 N/A 0.047±0.02
ENST00000539896 0.054±0.00 0.129±0.05 N/A 0.079±0.06

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001530 IEA lipopolysaccharide binding
GO:0001816 IEA cytokine production
GO:0001875 IEA lipopolysaccharide receptor activity
GO:0004930 TAS:IEA G-protein coupled receptor activity
GO:0004992 IDA platelet activating factor receptor activity
GO:0005543 IDA phospholipid binding
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006935 IEA chemotaxis
GO:0006954 IEA inflammatory response
GO:0006955 TAS immune response
GO:0007186 IMP:IEA G-protein coupled receptor signaling pathway
GO:0016020 IDA membrane
GO:0016021 NAS:IEA integral component of membrane
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0031663 IEA lipopolysaccharide-mediated signaling pathway
GO:0032496 IEA response to lipopolysaccharide
GO:0032959 IEA inositol trisphosphate biosynthetic process
GO:0048015 IDA phosphatidylinositol-mediated signaling
GO:0060333 TAS interferon-gamma-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042370 ptafr protein_coding Danio_rerio
ENSMUSG00000056529 Ptafr protein_coding Mus_musculus

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