ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: aprataxin and PNKP like factor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000169621 APLF 9606 + 2:68467561-68655576 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000303795 APLF-001 68467561-68580162 protein_coding
  ENST00000394342 APLF-201 68645822-68655576 protein_coding
  ENST00000445692 APLF-004 68467603-68580162 nonsense_mediated_decay
  ENST00000471727 APLF-002 68529638-68630724 processed_transcript
  ENST00000488585 APLF-005 68627880-68630872 processed_transcript
  ENST00000529851 APLF-006 68467572-68579257 nonsense_mediated_decay

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000303795ENST00000394342ENST00000471727ENST00000529851
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000303795 0.460±0.10 0.256±0.25 0.368±0.00 1.043±0.00 0.409±0.27
ENST00000394342 N/A 0.104±0.04 N/A N/A 0.032±0.00
ENST00000471727 N/A 0.115±0.00 N/A N/A 0.109±0.00
ENST00000529851 0.131±0.00 0.248±0.14 0.426±0.00 N/A 0.494±0.22

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0008I2 CIL_0008I2_0001 VISTA
CIL_0002DS CIL_0002DS_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000012 IMP single strand break repair
GO:0000166 IDA nucleotide binding
GO:0000737 IEA DNA catabolic process, endonucleolytic
GO:0003906 IDA DNA-(apurinic or apyrimidinic site) lyase activity
GO:0004520 IDA endodeoxyribonuclease activity
GO:0004930 IEA G-protein coupled receptor activity
GO:0004983 IEA neuropeptide Y receptor activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0005886 TAS plasma membrane
GO:0006302 IMP double-strand break repair
GO:0006974 IDA cellular response to DNA damage stimulus
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007218 IEA neuropeptide signaling pathway
GO:0008408 IDA 3'-5' exonuclease activity
GO:0016021 IEA integral component of membrane
GO:0035861 IDA site of double-strand break
GO:0045191 IEA regulation of isotype switching
GO:0046872 IEA metal ion binding
GO:0051106 IGI positive regulation of DNA ligation
GO:0090305 IDA nucleic acid phosphodiester bond hydrolysis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000086579 APLF (1 of 2) protein_coding Danio_rerio
ENSMUSG00000030051 Aplf protein_coding Mus_musculus

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