ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: tripartite motif containing 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000171206 TRIM8 9606 + 10:102644496-102658407 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000302424 TRIM8-001 102644496-102658407 protein_coding
  ENST00000462202 TRIM8-003 102644887-102656954 protein_coding
  ENST00000479004 TRIM8-004 102655281-102657087 processed_transcript
  ENST00000487927 TRIM8-002 102649219-102656969 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000302424ENST00000487927
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000302424 22.794±0.00 16.036±12.58 7.931±0.00 24.409±0.00 28.030±22.62
ENST00000487927 N/A 2.516±0.67 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0008MQ CIL_0008MQ_0001 VISTA
CIL_00065X CIL_00065X_0001 CGP
CIL_0001HP CIL_0001HP_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0008270 IEA:NAS zinc ion binding
GO:0016567 IEA protein ubiquitination
GO:0016605 IDA PML body
GO:0016874 IEA ligase activity
GO:0032897 IEA negative regulation of viral transcription
GO:0042802 IPI identical protein binding
GO:0042803 IPI protein homodimerization activity
GO:0043123 IDA positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0045087 IDA innate immune response
GO:0046597 IEA negative regulation of viral entry into host cell
GO:0046872 IEA metal ion binding
GO:0051091 IDA positive regulation of sequence-specific DNA binding transcription factor activity
GO:0051092 IDA positive regulation of NF-kappaB transcription factor activity
GO:1902187 IDA negative regulation of viral release from host cell

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000060729 trim8b protein_coding Danio_rerio
ENSDARG00000090512 trim8a protein_coding Danio_rerio
ENSMUSG00000025034 Trim8 protein_coding Mus_musculus

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