ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: Sp3 transcription factor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000172845 SP3 9606 - 2:173906459-173965702 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000310015 SP3-001 173906459-173965702 protein_coding
  ENST00000416195 SP3-002 173908530-173964553 protein_coding
  ENST00000418194 SP3-003 173908530-173964219 protein_coding
  ENST00000462904 SP3-007 173955817-173965310 processed_transcript
  ENST00000465379 SP3-004 173908532-173916832 retained_intron
  ENST00000483084 SP3-005 173956074-173963379 processed_transcript
  ENST00000490182 SP3-008 173956081-173964885 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000310015ENST00000416195ENST00000418194ENST00000465379
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000310015 N/A 1.437±1.69 N/A 1.281±0.00 1.244±0.53
ENST00000416195 0.710±0.00 4.750±1.15 5.043±0.00 10.444±0.00 5.220±2.85
ENST00000418194 0.408±0.00 4.002±3.20 N/A 1.980±0.00 4.660±2.01
ENST00000465379 N/A N/A N/A N/A 2.735±0.09

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0007OE CIL_0007OE_0001 UCNEbase
CIL_0004JD CIL_0004JD_0001 CGP
CIL_0008JW CIL_0008JW_0001 VISTA
CIL_0008K1 CIL_0008K1_0001 VISTA
CIL_0008S8 CIL_0008S8_0001 VISTA
CIL_0003II CIL_0003II_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000979 IEA RNA polymerase II core promoter sequence-specific DNA binding
GO:0000987 IEA core promoter proximal region sequence-specific DNA binding
GO:0001078 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001503 IEA ossification
GO:0001701 IEA in utero embryonic development
GO:0001779 IEA natural killer cell differentiation
GO:0001829 IEA trophectodermal cell differentiation
GO:0001889 IEA liver development
GO:0001892 IEA embryonic placenta development
GO:0003677 IEA DNA binding
GO:0003682 IEA chromatin binding
GO:0003690 IEA double-stranded DNA binding
GO:0005515 IPI protein binding
GO:0005634 IC nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0017053 IEA transcriptional repressor complex
GO:0030183 IEA B cell differentiation
GO:0030217 IEA T cell differentiation
GO:0030218 IEA erythrocyte differentiation
GO:0030219 IEA megakaryocyte differentiation
GO:0030224 IEA monocyte differentiation
GO:0030324 IEA lung development
GO:0030851 IEA granulocyte differentiation
GO:0043353 IEA enucleate erythrocyte differentiation
GO:0045892 IMP negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0046872 IEA metal ion binding
GO:0048596 IEA embryonic camera-type eye morphogenesis
GO:0048706 IEA embryonic skeletal system development
GO:0060136 IEA embryonic process involved in female pregnancy
GO:0060216 IEA definitive hemopoiesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000001549 sp3a protein_coding Danio_rerio
ENSDARG00000007812 sp3b protein_coding Danio_rerio
ENSMUSG00000027109 Sp3 protein_coding Mus_musculus

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