ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: adenylate cyclase 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000174233 ADCY6 9606 - 12:48766194-48789037 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000307885 ADCY6-002 48766329-48784129 protein_coding
  ENST00000357869 ADCY6-201 48766198-48783441 protein_coding
  ENST00000547260 ADCY6-005 48766194-48774496 retained_intron
  ENST00000548351 ADCY6-007 48771743-48774024 processed_transcript
  ENST00000548820 ADCY6-009 48777672-48778424 protein_coding
  ENST00000550422 ADCY6-003 48766198-48789037 protein_coding
  ENST00000551435 ADCY6-006 48776294-48778185 retained_intron
  ENST00000552090 ADCY6-008 48773943-48776484 processed_transcript
  ENST00000552099 ADCY6-004 48771257-48774754 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000307885ENST00000357869ENST00000547260ENST00000550422
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000307885 N/A 1.707±0.90 N/A 2.994±0.00 4.301±3.76
ENST00000357869 1.241±0.00 3.809±1.74 1.725±0.00 1.762±0.00 3.583±1.51
ENST00000547260 N/A N/A 2.657±0.00 N/A 1.798±0.78
ENST00000550422 1.101±0.00 N/A N/A N/A 2.262±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0003DH CIL_0003DH_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004016 IDA:IEA adenylate cyclase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005886 TAS plasma membrane
GO:0005929 IEA cilium
GO:0006112 TAS energy reserve metabolic process
GO:0006171 IDA cAMP biosynthetic process
GO:0006833 TAS water transport
GO:0007165 TAS signal transduction
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007189 TAS adenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0007193 TAS adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007202 TAS activation of phospholipase C activity
GO:0007212 IDA dopamine receptor signaling pathway
GO:0007268 TAS synaptic transmission
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0009190 IEA cyclic nucleotide biosynthetic process
GO:0010977 ISS negative regulation of neuron projection development
GO:0016020 ISS membrane
GO:0016021 IEA integral component of membrane
GO:0016849 IEA phosphorus-oxygen lyase activity
GO:0019901 ISS protein kinase binding
GO:0034199 TAS activation of protein kinase A activity
GO:0035556 IEA intracellular signal transduction
GO:0044281 TAS small molecule metabolic process
GO:0045087 TAS innate immune response
GO:0046872 IEA metal ion binding
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0055085 TAS transmembrane transport
GO:0071377 TAS cellular response to glucagon stimulus
GO:0071380 IDA cellular response to prostaglandin E stimulus
GO:0071870 IDA cellular response to catecholamine stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000027797 adcy6b protein_coding Danio_rerio
ENSDARG00000061445 adcy6a protein_coding Danio_rerio
ENSMUSG00000022994 Adcy6 protein_coding Mus_musculus

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