ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: adenylate cyclase 6
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000357869 ADCY6-201 ENSG00000174233 9606 - 12:48766198-48783441 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000357869
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000357869 1.241±0.00 3.809±1.74 1.725±0.00 1.762±0.00 3.583±1.51

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004016 IDA:IEA adenylate cyclase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005886 TAS plasma membrane
GO:0005929 IEA cilium
GO:0006112 TAS energy reserve metabolic process
GO:0006171 IDA cAMP biosynthetic process
GO:0006833 TAS water transport
GO:0007165 TAS signal transduction
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007189 TAS adenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0007193 TAS adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007202 TAS activation of phospholipase C activity
GO:0007212 IDA dopamine receptor signaling pathway
GO:0007268 TAS synaptic transmission
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0009190 IEA cyclic nucleotide biosynthetic process
GO:0010977 ISS negative regulation of neuron projection development
GO:0016020 ISS membrane
GO:0016021 IEA integral component of membrane
GO:0016849 IEA phosphorus-oxygen lyase activity
GO:0019901 ISS protein kinase binding
GO:0034199 TAS activation of protein kinase A activity
GO:0035556 IEA intracellular signal transduction
GO:0044281 TAS small molecule metabolic process
GO:0045087 TAS innate immune response
GO:0046872 IEA metal ion binding
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0055085 TAS transmembrane transport
GO:0071377 TAS cellular response to glucagon stimulus
GO:0071380 IDA cellular response to prostaglandin E stimulus
GO:0071870 IDA cellular response to catecholamine stimulus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000096224 Adcy6-201 protein_coding Mus_musculus 0 2625
ENSDART00000124333 adcy5-001 protein_coding Danio_rerio 0 579
ENSMUST00000020706 Adcy1-001 protein_coding Mus_musculus 0 237
ENSDART00000087823 adcy8-201 protein_coding Danio_rerio 0.00000000000004 86
ENSDART00000134139 adcy8-001 protein_coding Danio_rerio 0.00000000000004 86

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