ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: nuclear receptor subfamily 1, group D, member 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000174738 NR1D2 9606 + 3:23945260-23980618 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000312521 NR1D2-001 23945260-23980618 protein_coding
  ENST00000383773 NR1D2-002 23945375-23978497 nonsense_mediated_decay
  ENST00000468700 NR1D2-004 23954626-23962334 retained_intron
  ENST00000472780 NR1D2-005 23964764-23968013 retained_intron
  ENST00000492552 NR1D2-003 23946121-23977543 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHHSECHMVEC-DHUVECENST00000312521ENST00000383773ENST00000492552
Transcript ID HAoEC HHSEC HMVEC-D HUVEC
ENST00000312521 2.219±2.81 0.597±0.00 1.713±0.00 2.927±2.66
ENST00000383773 N/A N/A N/A 1.483±0.95
ENST00000492552 1.221±0.08 N/A 2.781±0.00 2.713±1.31

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0002EM CIL_0002EM_0002 CGP
CIL_0002VH CIL_0002VH_0002 CGP
CIL_00025B CIL_00025B_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001046 IDA core promoter sequence-specific DNA binding
GO:0003677 IEA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0003707 IEA steroid hormone receptor activity
GO:0004879 TAS ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 TAS:IEA regulation of transcription, DNA-templated
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0008270 IEA zinc ion binding
GO:0010467 TAS gene expression
GO:0019216 ISS regulation of lipid metabolic process
GO:0030522 TAS intracellular receptor signaling pathway
GO:0042752 ISS regulation of circadian rhythm
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0043565 IEA sequence-specific DNA binding
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0048511 IEA rhythmic process
GO:0050727 ISS regulation of inflammatory response
GO:0055088 ISS lipid homeostasis
GO:2000505 ISS regulation of energy homeostasis
GO:2001014 ISS regulation of skeletal muscle cell differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003820 nr1d2a protein_coding Danio_rerio
ENSDARG00000009594 nr1d2b protein_coding Danio_rerio
ENSMUSG00000021775 Nr1d2 protein_coding Mus_musculus

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