ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: F-box and WD repeat domain containing 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000174989 FBXW8 9606 + 12:116910956-117031148 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000309909 FBXW8-002 116910956-117028636 protein_coding
  ENST00000455858 FBXW8-001 116910965-117031148 protein_coding
  ENST00000551773 FBXW8-003 116978067-116985404 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000309909ENST00000455858
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000309909 0.953±0.07 2.626±0.36 1.280±0.00 1.823±0.00 2.133±1.05
ENST00000455858 0.256±0.00 1.911±0.36 N/A 2.493±0.00 1.648±0.76

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0005515 IPI:IEA protein binding
GO:0005794 IDA Golgi apparatus
GO:0007030 ISS Golgi organization
GO:0008283 IDA cell proliferation
GO:0016567 IEA protein ubiquitination
GO:0019005 IEA SCF ubiquitin ligase complex
GO:0031467 IDA Cul7-RING ubiquitin ligase complex
GO:0048471 IDA perinuclear region of cytoplasm
GO:0050775 ISS positive regulation of dendrite morphogenesis
GO:0060712 IEA spongiotrophoblast layer development
GO:0060716 IEA labyrinthine layer blood vessel development
GO:1990393 IDA 3M complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000079089 fbxw8 protein_coding Danio_rerio
ENSMUSG00000032867 Fbxw8 protein_coding Mus_musculus

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