ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000032867 Fbxw8 10090 - 5:118064965-118155464 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000049474 Fbxw8-001 118064965-118155464 protein_coding
  ENSMUST00000201545 Fbxw8-002 118077052-118155426 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000049474ENSMUST00000201545
Transcript ID C166 Tie2+ EC mES
ENSMUST00000049474 21.474±2.30 5.267±2.77 20.931±3.14
ENSMUST00000201545 N/A 11.831±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0004YT CIL_0004YT_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004842 ISS ubiquitin-protein transferase activity
GO:0005515 IPI protein binding
GO:0005794 ISS Golgi apparatus
GO:0006511 IC ubiquitin-dependent protein catabolic process
GO:0007030 ISS Golgi organization
GO:0008283 ISS cell proliferation
GO:0016567 ISS protein ubiquitination
GO:0019005 IPI SCF ubiquitin ligase complex
GO:0031467 IDA Cul7-RING ubiquitin ligase complex
GO:0048471 ISS perinuclear region of cytoplasm
GO:0050775 ISS positive regulation of dendrite morphogenesis
GO:0060712 IMP spongiotrophoblast layer development
GO:0060716 IMP labyrinthine layer blood vessel development
GO:1990393 ISS 3M complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000079089 fbxw8 protein_coding Danio_rerio
ENSG00000174989 FBXW8 F-box and WD repeat domain containing 8 protein_coding Homo_sapiens

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