ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: DNA-damage-inducible transcript 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000175197 DDIT3 9606 - 12:57516588-57520517 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000346473 DDIT3-001 57516593-57520517 protein_coding
  ENST00000547303 DDIT3-006 57516588-57520492 protein_coding
  ENST00000547526 DDIT3-004 57516953-57520511 protein_coding
  ENST00000551116 DDIT3-002 57516589-57520517 protein_coding
  ENST00000552740 DDIT3-005 57516809-57520511 protein_coding
  ENST00000618206 DDIT3-201 57516595-57520511 protein_coding
  ENST00000623876 DDIT3-003 57516593-57517743 TEC

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHUVECENST00000552740ENST00000618206
Transcript ID BECs HUVEC
ENST00000552740 N/A 37.568±12.20
ENST00000618206 24.986±0.00 24.958±0.00

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001955 IEA blood vessel maturation
GO:0003677 IDA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0003714 TAS transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005770 IEA late endosome
GO:0006355 IMP:IEA regulation of transcription, DNA-templated
GO:0006915 IEA apoptotic process
GO:0006974 TAS cellular response to DNA damage stimulus
GO:0006983 IEA ER overload response
GO:0006986 IDA response to unfolded protein
GO:0006987 TAS activation of signaling protein activity involved in unfolded protein response
GO:0007050 IEA cell cycle arrest
GO:0008134 IPI transcription factor binding
GO:0016055 IEA Wnt signaling pathway
GO:0030968 TAS endoplasmic reticulum unfolded protein response
GO:0032757 IMP positive regulation of interleukin-8 production
GO:0034976 IDA response to endoplasmic reticulum stress
GO:0042594 IEA response to starvation
GO:0042789 IDA mRNA transcription from RNA polymerase II promoter
GO:0043161 IDA proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043433 IDA negative regulation of sequence-specific DNA binding transcription factor activity
GO:0043525 IEA positive regulation of neuron apoptotic process
GO:0043565 IEA sequence-specific DNA binding
GO:0043620 TAS regulation of DNA-templated transcription in response to stress
GO:0044267 TAS cellular protein metabolic process
GO:0044324 ISS regulation of transcription involved in anterior/posterior axis specification
GO:0045454 IDA cell redox homeostasis
GO:0045662 IEA negative regulation of myoblast differentiation
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0051209 IEA release of sequestered calcium ion into cytosol
GO:0070059 IMP intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0090090 ISS negative regulation of canonical Wnt signaling pathway
GO:2000016 IDA negative regulation of determination of dorsal identity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000059836 ddit3 protein_coding Danio_rerio
ENSMUSG00000025408 Ddit3 protein_coding Mus_musculus

Loading