ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025408 Ddit3 10090 + 10:127290774-127296288 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000026475 Ddit3-001 127290774-127296288 protein_coding
  ENSMUST00000134686 Ddit3-003 127290794-127294582 retained_intron
  ENSMUST00000139091 Ddit3-002 127290793-127296065 protein_coding

Mus musculus Ensembl GRCm38

Genome
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Sequences
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Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000026475ENSMUST00000134686
Transcript ID C166 Tie2+ EC mES
ENSMUST00000026475 34.995±10.69 22.355±10.77 15.707±2.40
ENSMUST00000134686 N/A 3.605±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0003A8 CIL_0003A8_0002 CGP
CIL_0003A7 CIL_0003A7_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001955 IMP blood vessel maturation
GO:0003677 IDA DNA binding
GO:0003700 IMP sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IC nucleus
GO:0005770 IDA late endosome
GO:0006355 IMP regulation of transcription, DNA-templated
GO:0006915 IMP apoptotic process
GO:0006983 IMP ER overload response
GO:0006986 IEA response to unfolded protein
GO:0007050 IEA cell cycle arrest
GO:0008134 IEA transcription factor binding
GO:0016055 IEA Wnt signaling pathway
GO:0030968 IMP endoplasmic reticulum unfolded protein response
GO:0032757 IEA positive regulation of interleukin-8 production
GO:0034976 IDA response to endoplasmic reticulum stress
GO:0042594 IDA response to starvation
GO:0042789 IEA mRNA transcription from RNA polymerase II promoter
GO:0043161 IEA proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043433 IEA negative regulation of sequence-specific DNA binding transcription factor activity
GO:0043525 IMP positive regulation of neuron apoptotic process
GO:0043565 IEA sequence-specific DNA binding
GO:0044324 IDA regulation of transcription involved in anterior/posterior axis specification
GO:0045454 IEA cell redox homeostasis
GO:0045662 IMP negative regulation of myoblast differentiation
GO:0045892 IMP negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0051209 IMP release of sequestered calcium ion into cytosol
GO:0070059 IMP intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0090090 IDA negative regulation of canonical Wnt signaling pathway
GO:2000016 IDA negative regulation of determination of dorsal identity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000059836 ddit3 protein_coding Danio_rerio
ENSG00000175197 DDIT3 DNA-damage-inducible transcript 3 protein_coding Homo_sapiens

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