| Transcript ID | BECs | HAoEC | HHSEC | HMVEC-D | HUVEC |
|---|---|---|---|---|---|
| ENST00000311956 | 3.022±0.00 | 21.605±8.76 | 2.978±0.00 | 25.504±0.00 | 12.444±9.18 |
| ENST00000525488 | N/A | N/A | N/A | N/A | 5.028±0.13 |
| ENST00000527588 | N/A | N/A | N/A | N/A | 0.573±0.40 |
Gene Info | |||||
|---|---|---|---|---|---|
| Description: | Rho GTPase activating protein 1 | ||||
| Gene Accession | Gene Name | Tax ID | Strand | Position | Gene Biotype |
|
ENSG00000175220 |
ARHGAP1 | 9606 | - |
11:46677080-46700615 |
protein_coding |
| Transcript Accession | Transcript Name | Position | Transcript Biotype | ||
| ENST00000311956 |
ARHGAP1-001 | 46677080-46700599 | protein_coding | ||
| ENST00000524594 |
ARHGAP1-002 | 46695083-46700615 | retained_intron | ||
| ENST00000525488 |
ARHGAP1-006 | 46681069-46697284 | protein_coding | ||
| ENST00000526423 |
ARHGAP1-004 | 46678723-46681516 | retained_intron | ||
| ENST00000527588 |
ARHGAP1-005 | 46686747-46697572 | retained_intron | ||
| ENST00000528837 |
ARHGAP1-007 | 46679217-46696099 | protein_coding | ||
| ENST00000529960 |
ARHGAP1-003 | 46687691-46700603 | retained_intron | ||
Expression Patterns
|
Conserved Regions |
|---|
| Not located within a conserved region. |
Gene Ontology |
||
|---|---|---|
| GO ID | Evidence Type | GO Description |
| GO:0001726 | IEA | ruffle |
| GO:0005070 | TAS | SH3/SH2 adaptor activity |
| GO:0005100 | IDA | Rho GTPase activator activity |
| GO:0005515 | IPI | protein binding |
| GO:0005622 | IEA | intracellular |
| GO:0005829 | TAS | cytosol |
| GO:0005886 | IEA | plasma membrane |
| GO:0007165 | IEA | signal transduction |
| GO:0007264 | IDA | small GTPase mediated signal transduction |
| GO:0007266 | TAS | Rho protein signal transduction |
| GO:0009967 | TAS | positive regulation of signal transduction |
| GO:0017124 | IEA | SH3 domain binding |
| GO:0030675 | IEA | Rac GTPase activator activity |
| GO:0031252 | IEA | cell leading edge |
| GO:0032321 | IEA | positive regulation of Rho GTPase activity |
| GO:0032855 | IEA | positive regulation of Rac GTPase activity |
| GO:0043087 | IEA | regulation of GTPase activity |
| GO:0051056 | TAS | regulation of small GTPase mediated signal transduction |
| GO:0070062 | IDA | extracellular vesicular exosome |
Homologs | |||||
| ENSEMBL Accession | Gene Name | Description | Biotype | Species | |
|
ENSDARG00000024324
|
arhgap1 | protein_coding | Danio_rerio | ||
|
ENSMUSG00000027247
|
Arhgap1 | protein_coding | Mus_musculus | ||