ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: excision repair cross-complementation group 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000175595 ERCC4 9606 + 16:13920157-13952345 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000311895 ERCC4-001 13920157-13952345 protein_coding
  ENST00000389138 ERCC4-004 13932026-13948425 retained_intron
  ENST00000462862 ERCC4-002 13937764-13948004 nonsense_mediated_decay
  ENST00000573018 ERCC4-008 13934022-13935387 retained_intron
  ENST00000574194 ERCC4-007 13926552-13932239 nonsense_mediated_decay
  ENST00000574781 ERCC4-006 13927450-13930878 processed_transcript
  ENST00000575156 ERCC4-003 13920157-13933247 protein_coding
  ENST00000576348 ERCC4-005 13920191-13926801 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000311895ENST00000574781ENST00000575156ENST00000576348
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000311895 0.027±0.00 1.577±0.46 2.929±0.00 1.564±1.18
ENST00000574781 0.205±0.00 N/A N/A N/A
ENST00000575156 N/A N/A N/A 0.146±0.00
ENST00000576348 N/A N/A N/A 1.717±0.66

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0007DX CIL_0007DX_0001 CGP
CIL_0002RP CIL_0002RP_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000014 IBA single-stranded DNA endodeoxyribonuclease activity
GO:0000109 IDA nucleotide-excision repair complex
GO:0000110 IDA nucleotide-excision repair factor 1 complex
GO:0000712 IBA resolution of meiotic recombination intermediates
GO:0000718 TAS nucleotide-excision repair, DNA damage removal
GO:0000723 IMP telomere maintenance
GO:0000724 IMP double-strand break repair via homologous recombination
GO:0000737 IBA DNA catabolic process, endonucleolytic
GO:0000781 IDA chromosome, telomeric region
GO:0000784 IDA nuclear chromosome, telomeric region
GO:0001094 IEA TFIID-class transcription factor binding
GO:0003676 IEA nucleic acid binding
GO:0003677 IEA DNA binding
GO:0003684 IMP damaged DNA binding
GO:0003697 IDA single-stranded DNA binding
GO:0004518 IEA nuclease activity
GO:0004519 IEA endonuclease activity
GO:0004520 IDA endodeoxyribonuclease activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005669 IEA transcription factor TFIID complex
GO:0006281 IMP:IEA DNA repair
GO:0006283 TAS transcription-coupled nucleotide-excision repair
GO:0006289 IDA nucleotide-excision repair
GO:0006295 IMP nucleotide-excision repair, DNA incision, 3'-to lesion
GO:0006296 IMP nucleotide-excision repair, DNA incision, 5'-to lesion
GO:0008022 IPI protein C-terminus binding
GO:0009411 IMP response to UV
GO:0009650 IEA UV protection
GO:0010834 IMP telomere maintenance via telomere shortening
GO:0032205 IMP negative regulation of telomere maintenance
GO:0033683 IDA nucleotide-excision repair, DNA incision
GO:0043566 IDA structure-specific DNA binding
GO:0047485 IPI protein N-terminus binding
GO:1901255 IBA nucleotide-excision repair involved in interstrand cross-link repair

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014161 ercc4 protein_coding Danio_rerio
ENSMUSG00000022545 Ercc4 protein_coding Mus_musculus

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